Machado M - Search Results

1

Flexible 3D Cell-Based Platforms for the Discovery and Profiling of Novel Drugs Targeting Plasmodium Hepatic Infection.

Arez F, Rebelo SP, Fontinha D, Simão D, Martins TR, Machado M, Fischli C, Oeuvray C, Badolo L, Carrondo MJT, Rottmann M, Spangenberg T, Brito C, Greco B, Prudêncio M, Alves PM. Arez F, et al. Among authors: machado m. ACS Infect Dis. 2019 Nov 8;5(11):1831-1842. doi: 10.1021/acsinfecdis.9b00144. Epub 2019 Sep 13. ACS Infect Dis. 2019. PMID: 31479238

2

N-cinnamoylation of antimalarial classics: quinacrine analogues with decreased toxicity and dual-stage activity.

Gomes A, Pérez B, Albuquerque I, Machado M, Prudêncio M, Nogueira F, Teixeira C, Gomes P. Gomes A, et al. Among authors: machado m. ChemMedChem. 2014 Feb;9(2):305-10. doi: 10.1002/cmdc.201300459. Epub 2013 Dec 27. ChemMedChem. 2014. PMID: 24474655

3

Targeting the erythrocytic and liver stages of malaria parasites with s-triazine-based hybrids.

Rodrigues CA, Frade RF, Albuquerque IS, Perry MJ, Gut J, Machado M, Rosenthal PJ, Prudêncio M, Afonso CA, Moreira R. Rodrigues CA, et al. Among authors: machado m. ChemMedChem. 2015 May;10(5):883-90. doi: 10.1002/cmdc.201500011. Epub 2015 Mar 17. ChemMedChem. 2015. PMID: 25784585

4

N-Cinnamoylation of Antimalarial Classics: Effects of Using Acyl Groups Other than Cinnamoyl toward Dual-Stage Antimalarials.

Gomes A, Machado M, Lobo L, Nogueira F, Prudêncio M, Teixeira C, Gomes P. Gomes A, et al. Among authors: machado m. ChemMedChem. 2015 Aug;10(8):1344-9. doi: 10.1002/cmdc.201500164. Epub 2015 Jun 2. ChemMedChem. 2015. PMID: 26038181

5

Primaquine-pyrimidine hybrids: synthesis and dual-stage antiplasmodial activity.

Kaur H, Machado M, de Kock C, Smith P, Chibale K, Prudêncio M, Singh K. Kaur H, et al. Among authors: machado m. Eur J Med Chem. 2015 Aug 28;101:266-73. doi: 10.1016/j.ejmech.2015.06.045. Epub 2015 Jun 29. Eur J Med Chem. 2015. PMID: 26142491

6

Enantiopure Indolizinoindolones with in vitro Activity against Blood- and Liver-Stage Malaria Parasites.

Pereira NA, Monteiro Â, Machado M, Gut J, Molins E, Perry MJ, Dourado J, Moreira R, Rosenthal PJ, Prudêncio M, Santos MM. Pereira NA, et al. Among authors: machado m. ChemMedChem. 2015 Dec;10(12):2080-9. doi: 10.1002/cmdc.201500429. Epub 2015 Nov 3. ChemMedChem. 2015. PMID: 26525306

7

Reinvestigating Old Pharmacophores: Are 4-Aminoquinolines and Tetraoxanes Potential Two-Stage Antimalarials?

Terzić N, Konstantinović J, Tot M, Burojević J, Djurković-Djaković O, Srbljanović J, Štajner T, Verbić T, Zlatović M, Machado M, Albuquerque IS, Prudêncio M, Sciotti RJ, Pecic S, D'Alessandro S, Taramelli D, Šolaja BA. Terzić N, et al. Among authors: machado m. J Med Chem. 2016 Jan 14;59(1):264-81. doi: 10.1021/acs.jmedchem.5b01374. Epub 2015 Dec 18. J Med Chem. 2016. PMID: 26640981

8

Novel squaramides with in vitro liver stage antiplasmodial activity.

Ribeiro CJ, Espadinha M, Machado M, Gut J, Gonçalves LM, Rosenthal PJ, Prudêncio M, Moreira R, Santos MM. Ribeiro CJ, et al. Among authors: machado m. Bioorg Med Chem. 2016 Apr 15;24(8):1786-92. doi: 10.1016/j.bmc.2016.03.005. Epub 2016 Mar 3. Bioorg Med Chem. 2016. PMID: 26968650

9

Chloroquine-containing organoruthenium complexes are fast-acting multistage antimalarial agents.

Macedo TS, Colina-Vegas L, DA Paixão M, Navarro M, Barreto BC, Oliveira PC, Macambira SG, Machado M, Prudêncio M, D'Alessandro S, Basilico N, Moreira DR, Batista AA, Soares MB. Macedo TS, et al. Among authors: machado m. Parasitology. 2016 Oct;143(12):1543-56. doi: 10.1017/S0031182016001153. Epub 2016 Jul 21. Parasitology. 2016. PMID: 27439976

10

Probing the Azaaurone Scaffold against the Hepatic and Erythrocytic Stages of Malaria Parasites.

Carrasco MP, Machado M, Gonçalves L, Sharma M, Gut J, Lukens AK, Wirth DF, André V, Duarte MT, Guedes RC, Dos Santos DJ, Rosenthal PJ, Mazitschek R, Prudêncio M, Moreira R. Carrasco MP, et al. Among authors: machado m. ChemMedChem. 2016 Oct 6;11(19):2194-2204. doi: 10.1002/cmdc.201600327. Epub 2016 Aug 19. ChemMedChem. 2016. PMID: 27538856

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