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Page 1
Finding synergies for the 3Rs - Repeated Dose Toxicity testing: Report from an EPAA Partners' Forum.
Laroche C, Annys E, Bender H, Botelho D, Botham P, Brendler-Schwaab S, Clayton R, Corvaro M, Dal Negro G, Delannois F, Dent M, Desaintes C, Desprez B, Dhalluin S, Hartmann A, Hoffmann-Doerr S, Hubesch B, Irizar A, Manou I, Müller BP, Nadzialek S, Prieto P, Rasenberg M, Roggeband R, Rowan TG, Schutte K, van de Water B, Westmoreland C, Whelan M, Wilschut A, Zvonimir Z, Cronin MTD. Laroche C, et al. Among authors: hartmann a. Regul Toxicol Pharmacol. 2019 Nov;108:104470. doi: 10.1016/j.yrtph.2019.104470. Epub 2019 Aug 31. Regul Toxicol Pharmacol. 2019. PMID: 31479718 Free article.
The in vivo comet assay: use and status in genotoxicity testing.
Brendler-Schwaab S, Hartmann A, Pfuhler S, Speit G. Brendler-Schwaab S, et al. Among authors: hartmann a. Mutagenesis. 2005 Jul;20(4):245-54. doi: 10.1093/mutage/gei033. Epub 2005 May 17. Mutagenesis. 2005. PMID: 15899933 Review.
Genotoxicity evaluation of a valsartan-related complex N-nitroso-impurity.
Glowienke S, Onken U, Elhajouji A, Muthusamy S, Sangana R, Martus HJ, Bedman T, Hartmann A. Glowienke S, et al. Among authors: hartmann a. Regul Toxicol Pharmacol. 2022 Oct;134:105245. doi: 10.1016/j.yrtph.2022.105245. Epub 2022 Aug 18. Regul Toxicol Pharmacol. 2022. PMID: 35988810
Comprehensive review of genotoxicity data for diclofenac.
Hartmann A, Erkman L, Maremanda N, Elhajouji A, Martus HJ. Hartmann A, et al. Mutat Res Genet Toxicol Environ Mutagen. 2021 Jun;866:503347. doi: 10.1016/j.mrgentox.2021.503347. Epub 2021 Mar 10. Mutat Res Genet Toxicol Environ Mutagen. 2021. PMID: 33985691
Fourth International Workgroup on Genotoxicity testing: results of the in vivo Comet assay workgroup.
Burlinson B, Tice RR, Speit G, Agurell E, Brendler-Schwaab SY, Collins AR, Escobar P, Honma M, Kumaravel TS, Nakajima M, Sasaki YF, Thybaud V, Uno Y, Vasquez M, Hartmann A; In Vivo Comet Assay Workgroup, part of the Fourth International Workgroup on Genotoxicity Testing. Burlinson B, et al. Among authors: hartmann a. Mutat Res. 2007 Feb 3;627(1):31-5. doi: 10.1016/j.mrgentox.2006.08.011. Epub 2006 Nov 22. Mutat Res. 2007. PMID: 17118697
Shared Learnings on the New EMA First-in-Human and Early Clinical Trial Guideline: Proceedings From a DIAlogue Session at DIA Europe 2018.
van der Laan JW, Benson CT, Janssens W, Bos J, Stahl E, Brady JT, Wändel-Liminga U, Corriol-Rohou S, Forster R, Hartmann A, Pertel PE, Robertson SM, Silva-Lima B, Malik RE, Chibout SD. van der Laan JW, et al. Among authors: hartmann a. Ther Innov Regul Sci. 2020 Mar;54(2):462-467. doi: 10.1007/s43441-019-00077-3. Epub 2020 Jan 6. Ther Innov Regul Sci. 2020. PMID: 32072587 Clinical Trial.
3,475 results