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Page 1
Finding synergies for the 3Rs - Repeated Dose Toxicity testing: Report from an EPAA Partners' Forum.
Laroche C, Annys E, Bender H, Botelho D, Botham P, Brendler-Schwaab S, Clayton R, Corvaro M, Dal Negro G, Delannois F, Dent M, Desaintes C, Desprez B, Dhalluin S, Hartmann A, Hoffmann-Doerr S, Hubesch B, Irizar A, Manou I, Müller BP, Nadzialek S, Prieto P, Rasenberg M, Roggeband R, Rowan TG, Schutte K, van de Water B, Westmoreland C, Whelan M, Wilschut A, Zvonimir Z, Cronin MTD. Laroche C, et al. Among authors: rowan tg. Regul Toxicol Pharmacol. 2019 Nov;108:104470. doi: 10.1016/j.yrtph.2019.104470. Epub 2019 Aug 31. Regul Toxicol Pharmacol. 2019. PMID: 31479718 Free article.
Can acute dermal systemic toxicity tests be replaced with oral tests? A comparison of route-specific systemic toxicity and hazard classifications under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS).
Moore NP, Andrew DJ, Bjerke DL, Creton S, Dreher D, Holmes T, Prieto P, Seidle T, Rowan TG. Moore NP, et al. Among authors: rowan tg. Regul Toxicol Pharmacol. 2013 Jun;66(1):30-7. doi: 10.1016/j.yrtph.2013.02.005. Epub 2013 Feb 24. Regul Toxicol Pharmacol. 2013. PMID: 23461858
Finding synergies for 3Rs - Toxicokinetics and read-across: Report from an EPAA partners' Forum.
Laroche C, Aggarwal M, Bender H, Benndorf P, Birk B, Crozier J, Dal Negro G, De Gaetano F, Desaintes C, Gardner I, Hubesch B, Irizar A, John D, Kumar V, Lostia A, Manou I, Monshouwer M, Müller BP, Paini A, Reid K, Rowan T, Sachana M, Schutte K, Stirling C, Taalman R, van Aerts L, Weissenhorn R, Sauer UG. Laroche C, et al. Regul Toxicol Pharmacol. 2018 Nov;99:5-21. doi: 10.1016/j.yrtph.2018.08.006. Epub 2018 Aug 23. Regul Toxicol Pharmacol. 2018. PMID: 30144470 Free article.
Diminazene resistance in Trypanosoma congolense is not caused by reduced transport capacity but associated with reduced mitochondrial membrane potential.
Carruthers LV, Munday JC, Ebiloma GU, Steketee P, Jayaraman S, Campagnaro GD, Ungogo MA, Lemgruber L, Donachie AM, Rowan TG, Peter R, Morrison LJ, Barrett MP, De Koning HP. Carruthers LV, et al. Among authors: rowan tg. Mol Microbiol. 2021 Aug;116(2):564-588. doi: 10.1111/mmi.14733. Epub 2021 May 18. Mol Microbiol. 2021. PMID: 33932053 Free article.
The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing.
Begolo D, Vincent IM, Giordani F, Pöhner I, Witty MJ, Rowan TG, Bengaly Z, Gillingwater K, Freund Y, Wade RC, Barrett MP, Clayton C. Begolo D, et al. Among authors: rowan tg. PLoS Pathog. 2018 Sep 25;14(9):e1007315. doi: 10.1371/journal.ppat.1007315. eCollection 2018 Sep. PLoS Pathog. 2018. PMID: 30252911 Free PMC article.
Identification of a 4-fluorobenzyl l-valinate amide benzoxaborole (AN11736) as a potential development candidate for the treatment of Animal African Trypanosomiasis (AAT).
Akama T, Zhang YK, Freund YR, Berry P, Lee J, Easom EE, Jacobs RT, Plattner JJ, Witty MJ, Peter R, Rowan TG, Gillingwater K, Brun R, Nare B, Mercer L, Xu M, Wang J, Liang H. Akama T, et al. Among authors: rowan tg. Bioorg Med Chem Lett. 2018 Jan 1;28(1):6-10. doi: 10.1016/j.bmcl.2017.11.028. Epub 2017 Nov 20. Bioorg Med Chem Lett. 2018. PMID: 29169674 Free PMC article.
The animal trypanosomiases and their chemotherapy: a review.
Giordani F, Morrison LJ, Rowan TG, DE Koning HP, Barrett MP. Giordani F, et al. Among authors: rowan tg. Parasitology. 2016 Dec;143(14):1862-1889. doi: 10.1017/S0031182016001268. Epub 2016 Oct 10. Parasitology. 2016. PMID: 27719692 Free PMC article. Review.
71 results