Babon JJ - Search Results

1

Membrane-associated RING-CH (MARCH) proteins down-regulate cell surface expression of the interleukin-6 receptor alpha chain (IL6Rα).

Babon JJ, Stockwell D, DiRago L, Zhang JG, Laktyushin A, Villadangos J, Ching A, Ishido S, Hilton DJ, Alexander WS, Nicola NA. Babon JJ, et al. Biochem J. 2019 Oct 15;476(19):2869-2882. doi: 10.1042/BCJ20190577. Biochem J. 2019. PMID: 31488575

2

Backbone 1H, 13C and 15N assignments of the 25 kDa SPRY domain-containing SOCS box protein 2 (SSB-2).

Yao S, Masters SL, Zhang JG, Palmer KR, Babon JJ, Nicola NA, Nicholson SE, Norton RS. Yao S, et al. Among authors: babon jj. J Biomol NMR. 2005 Jan;31(1):69-70. doi: 10.1007/s10858-004-6924-6. J Biomol NMR. 2005. PMID: 15692743 No abstract available.

3

The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues.

Masters SL, Yao S, Willson TA, Zhang JG, Palmer KR, Smith BJ, Babon JJ, Nicola NA, Norton RS, Nicholson SE. Masters SL, et al. Among authors: babon jj. Nat Struct Mol Biol. 2006 Jan;13(1):77-84. doi: 10.1038/nsmb1034. Epub 2005 Dec 20. Nat Struct Mol Biol. 2006. PMID: 16369487

4

The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability.

Babon JJ, McManus EJ, Yao S, DeSouza DP, Mielke LA, Sprigg NS, Willson TA, Hilton DJ, Nicola NA, Baca M, Nicholson SE, Norton RS. Babon JJ, et al. Mol Cell. 2006 Apr 21;22(2):205-16. doi: 10.1016/j.molcel.2006.03.024. Mol Cell. 2006. PMID: 16630890 Free article.

5

Dynamics of the SPRY domain-containing SOCS box protein 2: flexibility of key functional loops.

Yao S, Liu MS, Masters SL, Zhang JG, Babon JJ, Nicola NA, Nicholson SE, Norton RS. Yao S, et al. Among authors: babon jj. Protein Sci. 2006 Dec;15(12):2761-72. doi: 10.1110/ps.062477806. Epub 2006 Nov 6. Protein Sci. 2006. PMID: 17088318 Free PMC article.

6

The SOCS box domain of SOCS3: structure and interaction with the elonginBC-cullin5 ubiquitin ligase.

Babon JJ, Sabo JK, Soetopo A, Yao S, Bailey MF, Zhang JG, Nicola NA, Norton RS. Babon JJ, et al. J Mol Biol. 2008 Sep 12;381(4):928-40. doi: 10.1016/j.jmb.2008.06.038. Epub 2008 Jun 20. J Mol Biol. 2008. PMID: 18590740 Free PMC article.

7

Deletion of the SOCS box of suppressor of cytokine signaling 3 (SOCS3) in embryonic stem cells reveals SOCS box-dependent regulation of JAK but not STAT phosphorylation.

Boyle K, Zhang JG, Nicholson SE, Trounson E, Babon JJ, McManus EJ, Nicola NA, Robb L. Boyle K, et al. Among authors: babon jj. Cell Signal. 2009 Mar;21(3):394-404. doi: 10.1016/j.cellsig.2008.11.002. Epub 2008 Nov 12. Cell Signal. 2009. PMID: 19056487 Free PMC article.

8

The SOCS box encodes a hierarchy of affinities for Cullin5: implications for ubiquitin ligase formation and cytokine signalling suppression.

Babon JJ, Sabo JK, Zhang JG, Nicola NA, Norton RS. Babon JJ, et al. J Mol Biol. 2009 Mar 20;387(1):162-74. doi: 10.1016/j.jmb.2009.01.024. J Mol Biol. 2009. PMID: 19385048 Free PMC article.

9

Neutrophils require SHP1 to regulate IL-1β production and prevent inflammatory skin disease.

Croker BA, Lewis RS, Babon JJ, Mintern JD, Jenne DE, Metcalf D, Zhang JG, Cengia LH, O'Donnell JA, Roberts AW. Croker BA, et al. Among authors: babon jj. J Immunol. 2011 Jan 15;186(2):1131-9. doi: 10.4049/jimmunol.1002702. Epub 2010 Dec 15. J Immunol. 2011. PMID: 21160041

10

Suppression of cytokine signaling by SOCS3: characterization of the mode of inhibition and the basis of its specificity.

Babon JJ, Kershaw NJ, Murphy JM, Varghese LN, Laktyushin A, Young SN, Lucet IS, Norton RS, Nicola NA. Babon JJ, et al. Immunity. 2012 Feb 24;36(2):239-50. doi: 10.1016/j.immuni.2011.12.015. Immunity. 2012. PMID: 22342841 Free PMC article.

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