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Human genome-edited hematopoietic stem cells phenotypically correct Mucopolysaccharidosis type I.
Gomez-Ospina N, Scharenberg SG, Mostrel N, Bak RO, Mantri S, Quadros RM, Gurumurthy CB, Lee C, Bao G, Suarez CJ, Khan S, Sawamoto K, Tomatsu S, Raj N, Attardi LD, Aurelian L, Porteus MH. Gomez-Ospina N, et al. Among authors: attardi ld. Nat Commun. 2019 Sep 6;10(1):4045. doi: 10.1038/s41467-019-11962-8. Nat Commun. 2019. PMID: 31492863 Free PMC article.
The Transactivation Domains of the p53 Protein.
Raj N, Attardi LD. Raj N, et al. Among authors: attardi ld. Cold Spring Harb Perspect Med. 2017 Jan 3;7(1):a026047. doi: 10.1101/cshperspect.a026047. Cold Spring Harb Perspect Med. 2017. PMID: 27864306 Free PMC article. Review.
p53 governs an AT1 differentiation programme in lung cancer suppression.
Kaiser AM, Gatto A, Hanson KJ, Zhao RL, Raj N, Ozawa MG, Seoane JA, Bieging-Rolett KT, Wang M, Li I, Trope WL, Liou DZ, Shrager JB, Plevritis SK, Newman AM, Van Rechem C, Attardi LD. Kaiser AM, et al. Among authors: attardi ld. Nature. 2023 Jul;619(7971):851-859. doi: 10.1038/s41586-023-06253-8. Epub 2023 Jul 19. Nature. 2023. PMID: 37468633 Free PMC article.
Spatial transcriptomic analysis drives PET imaging of tight junction protein expression in pancreatic cancer theranostics.
Wang J, Seo JW, Kare AJ, Schneider M, Pandrala M, Tumbale SK, Raie MN, Engudar G, Zhang N, Guo Y, Zhong X, Ferreira S, Wu B, Attardi LD, Pratx G, Iagaru A, Brunsing RL, Charville GW, Park WG, Ferrara KW. Wang J, et al. Among authors: attardi ld. Nat Commun. 2024 Dec 30;15(1):10751. doi: 10.1038/s41467-024-54761-6. Nat Commun. 2024. PMID: 39737976 Free PMC article.
Cancer: A piece of the p53 puzzle.
Bieging KT, Attardi LD. Bieging KT, et al. Among authors: attardi ld. Nature. 2015 Apr 2;520(7545):37-8. doi: 10.1038/nature14374. Epub 2015 Mar 18. Nature. 2015. PMID: 25799989 No abstract available.
Neat1 is a p53-inducible lincRNA essential for transformation suppression.
Mello SS, Sinow C, Raj N, Mazur PK, Bieging-Rolett K, Broz DK, Imam JFC, Vogel H, Wood LD, Sage J, Hirose T, Nakagawa S, Rinn J, Attardi LD. Mello SS, et al. Among authors: attardi ld. Genes Dev. 2017 Jun 1;31(11):1095-1108. doi: 10.1101/gad.284661.116. Epub 2017 Jul 11. Genes Dev. 2017. PMID: 28698299 Free PMC article.
A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer.
Mello SS, Valente LJ, Raj N, Seoane JA, Flowers BM, McClendon J, Bieging-Rolett KT, Lee J, Ivanochko D, Kozak MM, Chang DT, Longacre TA, Koong AC, Arrowsmith CH, Kim SK, Vogel H, Wood LD, Hruban RH, Curtis C, Attardi LD. Mello SS, et al. Among authors: attardi ld. Cancer Cell. 2017 Oct 9;32(4):460-473.e6. doi: 10.1016/j.ccell.2017.09.007. Cancer Cell. 2017. PMID: 29017057 Free PMC article.
122 results