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PARK14 PLA2G6 mutants are defective in preventing rotenone-induced mitochondrial dysfunction, ROS generation and activation of mitochondrial apoptotic pathway.
Chiu CC, Yeh TH, Lu CS, Huang YC, Cheng YC, Huang YZ, Weng YH, Liu YC, Lai SC, Chen YL, Chen YJ, Chen CL, Chen HY, Lin YW, Wang HL. Chiu CC, et al. Among authors: liu yc. Oncotarget. 2017 Sep 15;8(45):79046-79060. doi: 10.18632/oncotarget.20893. eCollection 2017 Oct 3. Oncotarget. 2017. PMID: 29108286 Free PMC article.
PARK14 (D331Y) PLA2G6 Causes Early-Onset Degeneration of Substantia Nigra Dopaminergic Neurons by Inducing Mitochondrial Dysfunction, ER Stress, Mitophagy Impairment and Transcriptional Dysregulation in a Knockin Mouse Model.
Chiu CC, Lu CS, Weng YH, Chen YL, Huang YZ, Chen RS, Cheng YC, Huang YC, Liu YC, Lai SC, Lin KJ, Lin YW, Chen YJ, Chen CL, Yeh TH, Wang HL. Chiu CC, et al. Among authors: liu yc. Mol Neurobiol. 2019 Jun;56(6):3835-3853. doi: 10.1007/s12035-018-1118-5. Epub 2018 Aug 8. Mol Neurobiol. 2019. PMID: 30088174
Upregulated Expression of MicroRNA-204-5p Leads to the Death of Dopaminergic Cells by Targeting DYRK1A-Mediated Apoptotic Signaling Cascade.
Chiu CC, Yeh TH, Chen RS, Chen HC, Huang YZ, Weng YH, Cheng YC, Liu YC, Cheng AJ, Lu YC, Chen YJ, Lin YW, Hsu CC, Chen YL, Lu CS, Wang HL. Chiu CC, et al. Among authors: liu yc. Front Cell Neurosci. 2019 Sep 13;13:399. doi: 10.3389/fncel.2019.00399. eCollection 2019. Front Cell Neurosci. 2019. PMID: 31572127 Free PMC article.
HCH6-1, an antagonist of formyl peptide receptor-1, exerts anti-neuroinflammatory and neuroprotective effects in cellular and animal models of Parkinson's disease.
Wang HL, Cheng YC, Yeh TH, Liu HF, Weng YH, Chen RS, Chen YC, Lu JC, Hwang TL, Wei KC, Liu YC, Wang YT, Hsu CC, Chiu TJ, Chiu CC. Wang HL, et al. Among authors: liu yc, liu hf. Biochem Pharmacol. 2023 Jun;212:115524. doi: 10.1016/j.bcp.2023.115524. Epub 2023 Mar 30. Biochem Pharmacol. 2023. PMID: 37001680
3,656 results