Immormino RM - Search Results

1

NECA derivatives exploit the paralog-specific properties of the site 3 side pocket of Grp94, the endoplasmic reticulum Hsp90.

Huck JD, Que NLS, Immormino RM, Shrestha L, Taldone T, Chiosis G, Gewirth DT. Huck JD, et al. Among authors: immormino rm. J Biol Chem. 2019 Nov 1;294(44):16010-16019. doi: 10.1074/jbc.RA119.009960. Epub 2019 Sep 9. J Biol Chem. 2019. PMID: 31501246 Free PMC article.

2

Structure of unliganded GRP94, the endoplasmic reticulum Hsp90. Basis for nucleotide-induced conformational change.

Dollins DE, Immormino RM, Gewirth DT. Dollins DE, et al. Among authors: immormino rm. J Biol Chem. 2005 Aug 26;280(34):30438-47. doi: 10.1074/jbc.M503761200. Epub 2005 Jun 11. J Biol Chem. 2005. PMID: 15951571 Free article.

3

Structural and quantum chemical studies of 8-aryl-sulfanyl adenine class Hsp90 inhibitors.

Immormino RM, Kang Y, Chiosis G, Gewirth DT. Immormino RM, et al. J Med Chem. 2006 Aug 10;49(16):4953-60. doi: 10.1021/jm060297x. J Med Chem. 2006. PMID: 16884307

4

Ligand-induced conformational shift in the N-terminal domain of GRP94, an Hsp90 chaperone.

Immormino RM, Dollins DE, Shaffer PL, Soldano KL, Walker MA, Gewirth DT. Immormino RM, et al. J Biol Chem. 2004 Oct 29;279(44):46162-71. doi: 10.1074/jbc.M405253200. Epub 2004 Aug 2. J Biol Chem. 2004. PMID: 15292259 Free article.

5

Identification of potent water soluble purine-scaffold inhibitors of the heat shock protein 90.

He H, Zatorska D, Kim J, Aguirre J, Llauger L, She Y, Wu N, Immormino RM, Gewirth DT, Chiosis G. He H, et al. Among authors: immormino rm. J Med Chem. 2006 Jan 12;49(1):381-90. doi: 10.1021/jm0508078. J Med Chem. 2006. PMID: 16392823

6

Structures of GRP94-nucleotide complexes reveal mechanistic differences between the hsp90 chaperones.

Dollins DE, Warren JJ, Immormino RM, Gewirth DT. Dollins DE, et al. Among authors: immormino rm. Mol Cell. 2007 Oct 12;28(1):41-56. doi: 10.1016/j.molcel.2007.08.024. Mol Cell. 2007. PMID: 17936703 Free PMC article.

7

Different poses for ligand and chaperone in inhibitor-bound Hsp90 and GRP94: implications for paralog-specific drug design.

Immormino RM, Metzger LE 4th, Reardon PN, Dollins DE, Blagg BS, Gewirth DT. Immormino RM, et al. J Mol Biol. 2009 May 22;388(5):1033-42. doi: 10.1016/j.jmb.2009.03.071. Epub 2009 Apr 8. J Mol Biol. 2009. PMID: 19361515 Free PMC article.

8

Structure of UDP-N-acetylglucosamine acyltransferase with a bound antibacterial pentadecapeptide.

Williams AH, Immormino RM, Gewirth DT, Raetz CR. Williams AH, et al. Among authors: immormino rm. Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):10877-82. doi: 10.1073/pnas.0604465103. Epub 2006 Jul 11. Proc Natl Acad Sci U S A. 2006. PMID: 16835299 Free PMC article.

9

A Variable Active Site Residue Influences the Kinetics of Response Regulator Phosphorylation and Dephosphorylation.

Immormino RM, Silversmith RE, Bourret RB. Immormino RM, et al. Biochemistry. 2016 Oct 4;55(39):5595-5609. doi: 10.1021/acs.biochem.6b00645. Epub 2016 Sep 19. Biochemistry. 2016. PMID: 27589219 Free PMC article.

10

MolProbity: all-atom structure validation for macromolecular crystallography.

Chen VB, Arendall WB 3rd, Headd JJ, Keedy DA, Immormino RM, Kapral GJ, Murray LW, Richardson JS, Richardson DC. Chen VB, et al. Among authors: immormino rm. Acta Crystallogr D Biol Crystallogr. 2010 Jan;66(Pt 1):12-21. doi: 10.1107/S0907444909042073. Epub 2009 Dec 21. Acta Crystallogr D Biol Crystallogr. 2010. PMID: 20057044 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

28 results

Search Page

Filters