Endothelial-to-mesenchymal transition shapes the atherosclerotic plaque and modulates macrophage function.
Helmke A, Casper J, Nordlohne J, David S, Haller H, Zeisberg EM, von Vietinghoff S.
Helmke A, et al.
FASEB J. 2019 Feb;33(2):2278-2289. doi: 10.1096/fj.201801238R. Epub 2018 Sep 27.
FASEB J. 2019.
PMID: 30260706
Endothelial cells can acquire a mesenchymal phenotype upon irritation [endothelial-to-mesenchymal transition (EndMT)]. ...Our data suggest that EndMT shapes macrophage and endothelial cell phenotypes, thus affecting internal atherosclerotic plaque in addition to surface st …
Endothelial cells can acquire a mesenchymal phenotype upon irritation [endothelial-to-mesenchymal transition (EndMT)]. ...Our data su …