Leedale J - Search Results

1

Preparation of Primary Rat Hepatocyte Spheroids Utilizing the Liquid-Overlay Technique.

Kyffin JA, Cox CR, Leedale J, Colley HE, Murdoch C, Mistry P, Webb SD, Sharma P. Kyffin JA, et al. Among authors: leedale j. Curr Protoc Toxicol. 2019 Sep;81(1):e87. doi: 10.1002/cptx.87. Curr Protoc Toxicol. 2019. PMID: 31529797 Free PMC article.

2

Characterisation of a functional rat hepatocyte spheroid model.

Kyffin JA, Sharma P, Leedale J, Colley HE, Murdoch C, Harding AL, Mistry P, Webb SD. Kyffin JA, et al. Among authors: leedale j. Toxicol In Vitro. 2019 Mar;55:160-172. doi: 10.1016/j.tiv.2018.12.014. Epub 2018 Dec 20. Toxicol In Vitro. 2019. PMID: 30578835 Free PMC article.

3

Multiscale modelling of drug transport and metabolism in liver spheroids.

Leedale JA, Kyffin JA, Harding AL, Colley HE, Murdoch C, Sharma P, Williams DP, Webb SD, Bearon RN. Leedale JA, et al. Interface Focus. 2020 Apr 6;10(2):20190041. doi: 10.1098/rsfs.2019.0041. Epub 2020 Feb 14. Interface Focus. 2020. PMID: 32194929 Free PMC article.

4

Impact of cell types and culture methods on the functionality of in vitro liver systems - A review of cell systems for hepatotoxicity assessment.

Kyffin JA, Sharma P, Leedale J, Colley HE, Murdoch C, Mistry P, Webb SD. Kyffin JA, et al. Among authors: leedale j. Toxicol In Vitro. 2018 Apr;48:262-275. doi: 10.1016/j.tiv.2018.01.023. Epub 2018 Feb 1. Toxicol In Vitro. 2018. PMID: 29408671 Free article. Review.

5

A Combined In Vitro/In Silico Approach to Identifying Off-Target Receptor Toxicity.

Leedale J, Sharkey KJ, Colley HE, Norton ÁM, Peeney D, Mason CL, Sathish JG, Murdoch C, Sharma P, Webb SD. Leedale J, et al. iScience. 2018 Jun 29;4:84-96. doi: 10.1016/j.isci.2018.05.012. Epub 2018 May 18. iScience. 2018. PMID: 30240756 Free PMC article.

6

Mathematical modelling of oxygen gradients in stem cell-derived liver tissue.

Leedale JA, Lucendo-Villarin B, Meseguer-Ripolles J, Kasarinaite A, Webb SD, Hay DC. Leedale JA, et al. PLoS One. 2021 Feb 8;16(2):e0244070. doi: 10.1371/journal.pone.0244070. eCollection 2021. PLoS One. 2021. PMID: 33556073 Free PMC article.

7

A mathematical investigation into the uptake kinetics of nanoparticles in vitro.

West H, Roberts F, Sweeney P, Walker-Samuel S, Leedale J, Colley H, Murdoch C, Shipley RJ, Webb S. West H, et al. Among authors: leedale j. PLoS One. 2021 Jul 22;16(7):e0254208. doi: 10.1371/journal.pone.0254208. eCollection 2021. PLoS One. 2021. PMID: 34292999 Free PMC article.

8

Modelling the impact of changes in the extracellular environment on the cytosolic free NAD+/NADH ratio during cell culture.

Kelly RA, Leedale J, Harrell A, Beard DA, Randle LE, Chadwick AE, Webb SD. Kelly RA, et al. Among authors: leedale j. PLoS One. 2018 Nov 29;13(11):e0207803. doi: 10.1371/journal.pone.0207803. eCollection 2018. PLoS One. 2018. PMID: 30496306 Free PMC article.

9

Systems Toxicology Approach to Identifying Paracetamol Overdose.

Mason CL, Leedale J, Tasoulis S, Jarman I, Antoine DJ, Webb SD. Mason CL, et al. Among authors: leedale j. CPT Pharmacometrics Syst Pharmacol. 2018 Jun;7(6):394-403. doi: 10.1002/psp4.12298. Epub 2018 Apr 18. CPT Pharmacometrics Syst Pharmacol. 2018. PMID: 29667370 Free PMC article.

10

Modelling changes in glutathione homeostasis as a function of quinone redox metabolism.

Kelly RA, Leedale J, Calleja D, Enoch SJ, Harrell A, Chadwick AE, Webb S. Kelly RA, et al. Among authors: leedale j. Sci Rep. 2019 Apr 19;9(1):6333. doi: 10.1038/s41598-019-42799-2. Sci Rep. 2019. PMID: 31004119 Free PMC article.

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