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Page 1
Trastuzumab-MMAU Antibody-Auristatin Conjugates: Valine-Glucoserine Linker with Stabilized Maleimide Conjugation Improves In Vivo Efficacy and Tolerability.
Goldberg SD, Satomaa T, Aina O, Aitio O, Burke K, Dudkin V, Geist B, Irrechukwu O, Hänninen AL, Heiskanen A, Helin J, Hiltunen JO, Kinyamu-Akunda J, Klein DM, Kohli N, Kotiranta T, Lähteenmäki T, Niemelä R, Pitkänen V, Pynnönen H, Rittase W, Wiley K, Zhou J, Saarinen J. Goldberg SD, et al. Among authors: pynnonen h. Mol Cancer Ther. 2024 Nov 4;23(11):1530-1543. doi: 10.1158/1535-7163.MCT-23-0591. Mol Cancer Ther. 2024. PMID: 38324296
Targeting CD33+ Acute Myeloid Leukemia with GLK-33, a Lintuzumab-Auristatin Conjugate with a Wide Therapeutic Window.
Satomaa T, Pynnönen H, Aitio O, Hiltunen JO, Pitkänen V, Lähteenmäki T, Kotiranta T, Heiskanen A, Hänninen AL, Niemelä R, Helin J, Kuusanmäki H, Vänttinen I, Rathod R, Nieminen AI, Yatkin E, Heckman CA, Kontro M, Saarinen J. Satomaa T, et al. Among authors: pynnonen h. Mol Cancer Ther. 2024 Aug 1;23(8):1073-1083. doi: 10.1158/1535-7163.MCT-23-0720. Mol Cancer Ther. 2024. PMID: 38561023
Quantitation of 4-O-methylglucuronic acid from plant cell walls.
Chong SL, Koutaniemi S, Virkki L, Pynnönen H, Tuomainen P, Tenkanen M. Chong SL, et al. Among authors: pynnonen h. Carbohydr Polym. 2013 Jan 16;91(2):626-30. doi: 10.1016/j.carbpol.2012.08.078. Epub 2012 Aug 30. Carbohydr Polym. 2013. PMID: 23121956