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Reply to 'H-STS, L-STS and KRJ-I are not authentic GEPNET cell lines'.
Alvarez MJ, Yan P, Alpaugh ML, Bowden M, Sicinska E, Zhou CW, Karan C, Realubit RB, Mundi PS, Grunn A, Jäger D, Chabot JA, Fojo AT, Oberstein PE, Hibshoosh H, Milsom JW, Kulke MH, Loda M, Chiosis G, Reidy-Lagunes DL, Califano A. Alvarez MJ, et al. Among authors: chiosis g. Nat Genet. 2019 Oct;51(10):1427-1428. doi: 10.1038/s41588-019-0509-5. Nat Genet. 2019. PMID: 31548719 Free PMC article. No abstract available.
Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90.
Moulick K, Ahn JH, Zong H, Rodina A, Cerchietti L, Gomes DaGama EM, Caldas-Lopes E, Beebe K, Perna F, Hatzi K, Vu LP, Zhao X, Zatorska D, Taldone T, Smith-Jones P, Alpaugh M, Gross SS, Pillarsetty N, Ku T, Lewis JS, Larson SM, Levine R, Erdjument-Bromage H, Guzman ML, Nimer SD, Melnick A, Neckers L, Chiosis G. Moulick K, et al. Among authors: chiosis g. Nat Chem Biol. 2011 Sep 25;7(11):818-26. doi: 10.1038/nchembio.670. Nat Chem Biol. 2011. PMID: 21946277 Free PMC article.
Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2.
Patel PD, Yan P, Seidler PM, Patel HJ, Sun W, Yang C, Que NS, Taldone T, Finotti P, Stephani RA, Gewirth DT, Chiosis G. Patel PD, et al. Among authors: chiosis g. Nat Chem Biol. 2013 Nov;9(11):677-84. doi: 10.1038/nchembio.1335. Epub 2013 Sep 1. Nat Chem Biol. 2013. PMID: 23995768 Free PMC article.
The epichaperome is an integrated chaperome network that facilitates tumour survival.
Rodina A, Wang T, Yan P, Gomes ED, Dunphy MP, Pillarsetty N, Koren J, Gerecitano JF, Taldone T, Zong H, Caldas-Lopes E, Alpaugh M, Corben A, Riolo M, Beattie B, Pressl C, Peter RI, Xu C, Trondl R, Patel HJ, Shimizu F, Bolaender A, Yang C, Panchal P, Farooq MF, Kishinevsky S, Modi S, Lin O, Chu F, Patil S, Erdjument-Bromage H, Zanzonico P, Hudis C, Studer L, Roboz GJ, Cesarman E, Cerchietti L, Levine R, Melnick A, Larson SM, Lewis JS, Guzman ML, Chiosis G. Rodina A, et al. Among authors: chiosis g. Nature. 2016 Oct 20;538(7625):397-401. doi: 10.1038/nature19807. Epub 2016 Oct 5. Nature. 2016. PMID: 27706135 Free PMC article.
HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons.
Kishinevsky S, Wang T, Rodina A, Chung SY, Xu C, Philip J, Taldone T, Joshi S, Alpaugh ML, Bolaender A, Gutbier S, Sandhu D, Fattahi F, Zimmer B, Shah SK, Chang E, Inda C, Koren J 3rd, Saurat NG, Leist M, Gross SS, Seshan VE, Klein C, Tomishima MJ, Erdjument-Bromage H, Neubert TA, Henrickson RC, Chiosis G, Studer L. Kishinevsky S, et al. Among authors: chiosis g. Nat Commun. 2018 Oct 19;9(1):4345. doi: 10.1038/s41467-018-06486-6. Nat Commun. 2018. PMID: 30341316 Free PMC article.
A Chemical Biology Approach to the Chaperome in Cancer-HSP90 and Beyond.
Taldone T, Wang T, Rodina A, Pillarsetty NVK, Digwal CS, Sharma S, Yan P, Joshi S, Pagare PP, Bolaender A, Roboz GJ, Guzman ML, Chiosis G. Taldone T, et al. Among authors: chiosis g. Cold Spring Harb Perspect Biol. 2020 Apr 1;12(4):a034116. doi: 10.1101/cshperspect.a034116. Cold Spring Harb Perspect Biol. 2020. PMID: 30936118 Free PMC article. Review.
Paradigms for Precision Medicine in Epichaperome Cancer Therapy.
Pillarsetty N, Jhaveri K, Taldone T, Caldas-Lopes E, Punzalan B, Joshi S, Bolaender A, Uddin MM, Rodina A, Yan P, Ku A, Ku T, Shah SK, Lyashchenko S, Burnazi E, Wang T, Lecomte N, Janjigian Y, Younes A, Batlevi CW, Guzman ML, Roboz GJ, Koziorowski J, Zanzonico P, Alpaugh ML, Corben A, Modi S, Norton L, Larson SM, Lewis JS, Chiosis G, Gerecitano JF, Dunphy MPS. Pillarsetty N, et al. Among authors: chiosis g. Cancer Cell. 2019 Nov 11;36(5):559-573.e7. doi: 10.1016/j.ccell.2019.09.007. Epub 2019 Oct 24. Cancer Cell. 2019. PMID: 31668946 Free PMC article.
The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction.
Inda MC, Joshi S, Wang T, Bolaender A, Gandu S, Koren Iii J, Che AY, Taldone T, Yan P, Sun W, Uddin M, Panchal P, Riolo M, Shah S, Barlas A, Xu K, Chan LYL, Gruzinova A, Kishinevsky S, Studer L, Fossati V, Noggle SA, White JR, de Stanchina E, Sequeira S, Anthoney KH, Steele JW, Manova-Todorova K, Patil S, Dunphy MP, Pillarsetty N, Pereira AC, Erdjument-Bromage H, Neubert TA, Rodina A, Ginsberg SD, De Marco Garcia N, Luo W, Chiosis G. Inda MC, et al. Among authors: chiosis g. Nat Commun. 2020 Jan 16;11(1):319. doi: 10.1038/s41467-019-14082-5. Nat Commun. 2020. PMID: 31949159 Free PMC article.
179 results