Zenke FT - Search Results

1

Therapeutic Implications of p53 Status on Cancer Cell Fate Following Exposure to Ionizing Radiation and the DNA-PK Inhibitor M3814.

Sun Q, Guo Y, Liu X, Czauderna F, Carr MI, Zenke FT, Blaukat A, Vassilev LT. Sun Q, et al. Among authors: zenke ft. Mol Cancer Res. 2019 Dec;17(12):2457-2468. doi: 10.1158/1541-7786.MCR-19-0362. Epub 2019 Sep 24. Mol Cancer Res. 2019. PMID: 31551253

2

Overcoming hypoxia-induced tumor radioresistance in non-small cell lung cancer by targeting DNA-dependent protein kinase in combination with carbon ion irradiation.

Klein C, Dokic I, Mairani A, Mein S, Brons S, Häring P, Haberer T, Jäkel O, Zimmermann A, Zenke F, Blaukat A, Debus J, Abdollahi A. Klein C, et al. Radiat Oncol. 2017 Dec 29;12(1):208. doi: 10.1186/s13014-017-0939-0. Radiat Oncol. 2017. PMID: 29287602 Free PMC article.

3

Modeling the Effect of Hypoxia and DNA Repair Inhibition on Cell Survival After Photon Irradiation.

Liew H, Klein C, Zenke FT, Abdollahi A, Debus J, Dokic I, Mairani A. Liew H, et al. Among authors: zenke ft. Int J Mol Sci. 2019 Nov 30;20(23):6054. doi: 10.3390/ijms20236054. Int J Mol Sci. 2019. PMID: 31801300 Free PMC article.

4

DNA-PK Inhibitor, M3814, as a New Combination Partner of Mylotarg in the Treatment of Acute Myeloid Leukemia.

Carr MI, Zimmermann A, Chiu LY, Zenke FT, Blaukat A, Vassilev LT. Carr MI, et al. Among authors: zenke ft. Front Oncol. 2020 Feb 13;10:127. doi: 10.3389/fonc.2020.00127. eCollection 2020. Front Oncol. 2020. PMID: 32117773 Free PMC article.

5

Pharmacologic Inhibitor of DNA-PK, M3814, Potentiates Radiotherapy and Regresses Human Tumors in Mouse Models.

Zenke FT, Zimmermann A, Sirrenberg C, Dahmen H, Kirkin V, Pehl U, Grombacher T, Wilm C, Fuchss T, Amendt C, Vassilev LT, Blaukat A. Zenke FT, et al. Mol Cancer Ther. 2020 May;19(5):1091-1101. doi: 10.1158/1535-7163.MCT-19-0734. Epub 2020 Mar 27. Mol Cancer Ther. 2020. PMID: 32220971

6

Novel and Highly Potent ATR Inhibitor M4344 Kills Cancer Cells With Replication Stress, and Enhances the Chemotherapeutic Activity of Widely Used DNA Damaging Agents.

Jo U, Senatorov IS, Zimmermann A, Saha LK, Murai Y, Kim SH, Rajapakse VN, Elloumi F, Takahashi N, Schultz CW, Thomas A, Zenke FT, Pommier Y. Jo U, et al. Among authors: zenke ft. Mol Cancer Ther. 2021 Aug;20(8):1431-1441. doi: 10.1158/1535-7163.MCT-20-1026. Epub 2021 May 27. Mol Cancer Ther. 2021. PMID: 34045232 Free PMC article.

7

DNA-PK inhibitor peposertib enhances p53-dependent cytotoxicity of DNA double-strand break inducing therapy in acute leukemia.

Haines E, Nishida Y, Carr MI, Montoya RH, Ostermann LB, Zhang W, Zenke FT, Blaukat A, Andreeff M, Vassilev LT. Haines E, et al. Among authors: zenke ft. Sci Rep. 2021 Jun 9;11(1):12148. doi: 10.1038/s41598-021-90500-3. Sci Rep. 2021. PMID: 34108527 Free PMC article.

8

DNA-PK Inhibitor Peposertib Amplifies Radiation-Induced Inflammatory Micronucleation and Enhances TGFβ/PD-L1 Targeted Cancer Immunotherapy.

Carr MI, Chiu LY, Guo Y, Xu C, Lazorchak AS, Yu H, Qin G, Qi J, Marelli B, Lan Y, Sun Q, Czauderna F, Zenke FT, Blaukat A, Vassilev LT. Carr MI, et al. Among authors: zenke ft. Mol Cancer Res. 2022 Apr 1;20(4):568-582. doi: 10.1158/1541-7786.MCR-21-0612. Mol Cancer Res. 2022. PMID: 34980594 Free PMC article.

9

A New Class of Selective ATM Inhibitors as Combination Partners of DNA Double-Strand Break Inducing Cancer Therapies.

Zimmermann A, Zenke FT, Chiu LY, Dahmen H, Pehl U, Fuchss T, Grombacher T, Blume B, Vassilev LT, Blaukat A. Zimmermann A, et al. Among authors: zenke ft. Mol Cancer Ther. 2022 Jun 1;21(6):859-870. doi: 10.1158/1535-7163.MCT-21-0934. Mol Cancer Ther. 2022. PMID: 35405736 Free PMC article.

10

The Role of ATR Inhibitors in Ovarian Cancer: Investigating Predictive Biomarkers of Response.

Bradbury A, Zenke FT, Curtin NJ, Drew Y. Bradbury A, et al. Among authors: zenke ft. Cells. 2022 Aug 1;11(15):2361. doi: 10.3390/cells11152361. Cells. 2022. PMID: 35954206 Free PMC article.

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