Liu M - Search Results

1

Discovery of Novel Aryl Carboxamide Derivatives as Hypoxia-Inducible Factor 1α Signaling Inhibitors with Potent Activities of Anticancer Metastasis.

Liu M, Liang Y, Zhu Z, Wang J, Cheng X, Cheng J, Xu B, Li R, Liu X, Wang Y. Liu M, et al. Among authors: liu x. J Med Chem. 2019 Oct 24;62(20):9299-9314. doi: 10.1021/acs.jmedchem.9b01313. Epub 2019 Oct 4. J Med Chem. 2019. PMID: 31556611

2

Potent Antitumor Activities and Structure Basis of the Chiral β-Lactam Bridged Analogue of Combretastatin A-4 Binding to Tubulin.

Zhou P, Liu Y, Zhou L, Zhu K, Feng K, Zhang H, Liang Y, Jiang H, Luo C, Liu M, Wang Y. Zhou P, et al. Among authors: liu y, liu m. J Med Chem. 2016 Nov 23;59(22):10329-10334. doi: 10.1021/acs.jmedchem.6b01268. Epub 2016 Nov 14. J Med Chem. 2016. PMID: 27805821

3

Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.

Zhou P, Liang Y, Zhang H, Jiang H, Feng K, Xu P, Wang J, Wang X, Ding K, Luo C, Liu M, Wang Y. Zhou P, et al. Among authors: liu m. Eur J Med Chem. 2018 Jan 20;144:817-842. doi: 10.1016/j.ejmech.2017.12.004. Epub 2017 Dec 7. Eur J Med Chem. 2018. PMID: 29306206

4

Discovery and SARs of 5-Chloro-N⁴-phenyl-N²-(pyridin-2-yl)pyrimidine-2,4-diamine Derivatives as Oral Available and Dual CDK 6 and 9 Inhibitors with Potent Antitumor Activity.

Wang Y, Chen X, Yan Y, Zhu X, Liu M, Liu X. Wang Y, et al. Among authors: liu x, liu m. J Med Chem. 2020 Mar 26;63(6):3327-3347. doi: 10.1021/acs.jmedchem.9b02121. Epub 2020 Mar 12. J Med Chem. 2020. PMID: 32129996

5

Design, synthesis and antitumor evaluation of novel chiral diaryl substituted azetidin-2-one derivatives as tubulin polymerization inhibitors.

Liang Y, Zhang M, Zhou P, Liu M, Li J, Wang Y. Liang Y, et al. Among authors: liu m. Bioorg Chem. 2021 Oct;115:105239. doi: 10.1016/j.bioorg.2021.105239. Epub 2021 Aug 8. Bioorg Chem. 2021. PMID: 34399321

6

Design, synthesis, and biological evaluation of hydantoin bridged analogues of combretastatin A-4 as potential anticancer agents.

Zhang M, Liang YR, Li H, Liu MM, Wang Y. Zhang M, et al. Among authors: liu mm. Bioorg Med Chem. 2017 Dec 15;25(24):6623-6634. doi: 10.1016/j.bmc.2017.10.045. Epub 2017 Nov 1. Bioorg Med Chem. 2017. PMID: 29126741

7

Discovery and In Vivo Anti-inflammatory Activity Evaluation of a Novel Non-peptidyl Non-covalent Cathepsin C Inhibitor.

Chen X, Yan Y, Zhang Z, Zhang F, Liu M, Du L, Zhang H, Shen X, Zhao D, Shi JB, Liu X. Chen X, et al. Among authors: liu x, liu m. J Med Chem. 2021 Aug 26;64(16):11857-11885. doi: 10.1021/acs.jmedchem.1c00104. Epub 2021 Aug 10. J Med Chem. 2021. PMID: 34374541

8

Discovery and Anti-Inflammatory Activity Evaluation of a Novel CDK8 Inhibitor through Upregulation of IL-10 for the Treatment of Inflammatory Bowel Disease In Vivo.

Yan Y, Xing C, Xiao Y, Shen X, Zhang Z, He C, Shi JB, Liu M, Liu X. Yan Y, et al. Among authors: liu x, liu m. J Med Chem. 2022 May 26;65(10):7334-7362. doi: 10.1021/acs.jmedchem.2c00356. Epub 2022 May 10. J Med Chem. 2022. PMID: 35536548

9

Design and synthesis of novel substituted naphthyridines as potential c-Met kinase inhibitors based on MK-2461.

Wu JF, Liu MM, Huang SX, Wang Y. Wu JF, et al. Bioorg Med Chem Lett. 2015 Aug 15;25(16):3251-5. doi: 10.1016/j.bmcl.2015.05.082. Epub 2015 May 31. Bioorg Med Chem Lett. 2015. PMID: 26077488

10

AMSP-30 m as a novel HIF-1α inhibitor attenuates the development and severity of adjuvant-induced arthritis in rats: Impacts on synovial apoptosis, synovial angiogenesis and sonic hedgehog signaling pathway.

Meng B, Liu FY, Liu MM, Yu LC, Zhang WT, Zhou MY, Liu SY, Li R, Cai L. Meng B, et al. Int Immunopharmacol. 2022 Feb;103:108467. doi: 10.1016/j.intimp.2021.108467. Epub 2021 Dec 20. Int Immunopharmacol. 2022. PMID: 34933161

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