Lam KW - Search Results

1

Insights on the synthesis of asymmetric curcumin derivatives and their biological activities.

Khor PY, Mohd Aluwi MFF, Rullah K, Lam KW. Khor PY, et al. Among authors: lam kw. Eur J Med Chem. 2019 Dec 1;183:111704. doi: 10.1016/j.ejmech.2019.111704. Epub 2019 Sep 16. Eur J Med Chem. 2019. PMID: 31557608 Review.

2

Synthesis and docking studies of 2,4,6-trihydroxy-3-geranylacetophenone analogs as potential lipoxygenase inhibitor.

Ng CH, Rullah K, Aluwi MF, Abas F, Lam KW, Ismail IS, Narayanaswamy R, Jamaludin F, Shaari K. Ng CH, et al. Among authors: lam kw. Molecules. 2014 Aug 5;19(8):11645-59. doi: 10.3390/molecules190811645. Molecules. 2014. PMID: 25100256 Free PMC article.

3

Nitric oxide inhibitory activity and antioxidant evaluations of 2-benzoyl-6-benzylidenecyclohexanone analogs, a novel series of curcuminoid and diarylpentanoid derivatives.

Leong SW, Mohd Faudzi SM, Abas F, Mohd Aluwi MF, Rullah K, Lam KW, Abdul Bahari MN, Ahmad S, Tham CL, Shaari K, Lajis NH. Leong SW, et al. Among authors: lam kw. Bioorg Med Chem Lett. 2015 Aug 15;25(16):3330-7. doi: 10.1016/j.bmcl.2015.05.056. Epub 2015 May 30. Bioorg Med Chem Lett. 2015. PMID: 26071636

4

Synthesis of unsymmetrical monocarbonyl curcumin analogues with potent inhibition on prostaglandin E2 production in LPS-induced murine and human macrophages cell lines.

Mohd Aluwi MFF, Rullah K, Yamin BM, Leong SW, Abdul Bahari MN, Lim SJ, Mohd Faudzi SM, Jalil J, Abas F, Mohd Fauzi N, Ismail NH, Jantan I, Lam KW. Mohd Aluwi MFF, et al. Among authors: lam kw. Bioorg Med Chem Lett. 2016 May 15;26(10):2531-2538. doi: 10.1016/j.bmcl.2016.03.092. Epub 2016 Mar 26. Bioorg Med Chem Lett. 2016. PMID: 27040659

5

Effects of Tocotrienols on Insulin Secretion-Associated Genes Expression of Rat Pancreatic Islets in a Dynamic Culture.

Chia LL, Jantan I, Chua KH, Lam KW, Rullah K, Aluwi MF. Chia LL, et al. Among authors: lam kw. Front Pharmacol. 2016 Aug 30;7:291. doi: 10.3389/fphar.2016.00291. eCollection 2016. Front Pharmacol. 2016. PMID: 27625609 Free PMC article.

6

In vitro and in silico evaluations of diarylpentanoid series as α-glucosidase inhibitor.

Leong SW, Abas F, Lam KW, Yusoff K. Leong SW, et al. Among authors: lam kw. Bioorg Med Chem Lett. 2018 Feb 1;28(3):302-309. doi: 10.1016/j.bmcl.2017.12.048. Epub 2017 Dec 23. Bioorg Med Chem Lett. 2018. PMID: 29292226

7

Hits-to-Lead Optimization of the Natural Compound 2,4,6-Trihydroxy-3-geranyl-acetophenone (tHGA) as a Potent LOX Inhibitor: Synthesis, Structure-Activity Relationship (SAR) Study, and Computational Assignment.

Ng CH, Rullah K, Abas F, Lam KW, Ismail IS, Jamaludin F, Shaari K. Ng CH, et al. Among authors: lam kw. Molecules. 2018 Sep 30;23(10):2509. doi: 10.3390/molecules23102509. Molecules. 2018. PMID: 30274341 Free PMC article.

8

Recent progress in small molecule agents for the targeted therapy of triple-negative breast cancer.

Islam R, Lam KW. Islam R, et al. Among authors: lam kw. Eur J Med Chem. 2020 Dec 1;207:112812. doi: 10.1016/j.ejmech.2020.112812. Epub 2020 Sep 6. Eur J Med Chem. 2020. PMID: 32937283 Review.

9

Flavonoid diversity and roles in the lipopolysaccharide-mediated inflammatory response of monocytes and macrophages.

Rullah K, Shamsudin NF, Koeberle A, Tham CL, Fasihi Mohd Aluwi MF, Leong SW, Jantan I, Lam KW. Rullah K, et al. Among authors: lam kw. Future Med Chem. 2024 Jan;16(1):75-99. doi: 10.4155/fmc-2023-0174. Epub 2024 Jan 11. Future Med Chem. 2024. PMID: 38205612 Review.

10

Inhibitory Effect of (2S)-Pinocembrin From Goniothalamus macrophyllus on the Prostaglandin E₂ Production in Macrophage Cell Lines: In Vitro and In Silico Studies.

Teruna HY, Rullah K, Hendra R, Utami R, Islami D, Mohd Faudzi SM, Mohd Aluwi MFF, Lam KW. Teruna HY, et al. Among authors: lam kw. Adv Pharmacol Pharm Sci. 2024 Oct 30;2024:8811022. doi: 10.1155/2024/8811022. eCollection 2024. Adv Pharmacol Pharm Sci. 2024. PMID: 39512302 Free PMC article.

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