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A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels.
Reddy K, Jenquin JR, McConnell OL, Cleary JD, Richardson JI, Pinto BS, Haerle MC, Delgado E, Planco L, Nakamori M, Wang ET, Berglund JA. Reddy K, et al. Among authors: nakamori m. Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):20991-21000. doi: 10.1073/pnas.1901893116. Epub 2019 Sep 30. Proc Natl Acad Sci U S A. 2019. PMID: 31570586 Free PMC article.
Reducing levels of toxic RNA with small molecules.
Coonrod LA, Nakamori M, Wang W, Carrell S, Hilton CL, Bodner MJ, Siboni RB, Docter AG, Haley MM, Thornton CA, Berglund JA. Coonrod LA, et al. Among authors: nakamori m. ACS Chem Biol. 2013 Nov 15;8(11):2528-37. doi: 10.1021/cb400431f. Epub 2013 Sep 27. ACS Chem Biol. 2013. PMID: 24028068 Free PMC article.
[Therapeutic development in myotonic dystrophy].
Takahashi MP, Nakamori M, Mochizuki H. Takahashi MP, et al. Among authors: nakamori m. Rinsho Shinkeigaku. 2014;54(12):1077-9. doi: 10.5692/clinicalneurol.54.1077. Rinsho Shinkeigaku. 2014. PMID: 25519965 Review. Japanese.
Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy.
Freyermuth F, Rau F, Kokunai Y, Linke T, Sellier C, Nakamori M, Kino Y, Arandel L, Jollet A, Thibault C, Philipps M, Vicaire S, Jost B, Udd B, Day JW, Duboc D, Wahbi K, Matsumura T, Fujimura H, Mochizuki H, Deryckere F, Kimura T, Nukina N, Ishiura S, Lacroix V, Campan-Fournier A, Navratil V, Chautard E, Auboeuf D, Horie M, Imoto K, Lee KY, Swanson MS, de Munain AL, Inada S, Itoh H, Nakazawa K, Ashihara T, Wang E, Zimmer T, Furling D, Takahashi MP, Charlet-Berguerand N. Freyermuth F, et al. Among authors: nakamori m. Nat Commun. 2016 Apr 11;7:11067. doi: 10.1038/ncomms11067. Nat Commun. 2016. PMID: 27063795 Free PMC article.
331 results