Kandel ES - Search Results

1

The role of polo-like kinase 3 in the response of BRAF-mutant cells to targeted anticancer therapies.

Babagana M, Kichina JV, Slabodkin H, Johnson S, Maslov A, Brown L, Attwood K, Nikiforov MA, Kandel ES. Babagana M, et al. Among authors: kandel es. Mol Carcinog. 2020 Jan;59(1):5-14. doi: 10.1002/mc.23123. Epub 2019 Sep 30. Mol Carcinog. 2020. PMID: 31571292 Free PMC article.

2

Apoptosis inhibitor as a suppressor of tumor progression: expression of Bcl-2 eliminates selective advantages for p53-deficient cells in the tumor.

Gurova KV, Kwek SS, Koman IE, Komarov AP, Kandel E, Nikiforov MA, Gudkov AV. Gurova KV, et al. Cancer Biol Ther. 2002 Jan-Feb;1(1):39-44. doi: 10.4161/cbt.1.1.39. Cancer Biol Ther. 2002. PMID: 12170763 Free article.

3

The role of PAK-1 in activation of MAP kinase cascade and oncogenic transformation by Akt.

Somanath PR, Vijai J, Kichina JV, Byzova T, Kandel ES. Somanath PR, et al. Among authors: kandel es. Oncogene. 2009 Jun 25;28(25):2365-9. doi: 10.1038/onc.2009.114. Epub 2009 May 4. Oncogene. 2009. PMID: 19421139 Free PMC article.

4

PAK1 as a therapeutic target.

Kichina JV, Goc A, Al-Husein B, Somanath PR, Kandel ES. Kichina JV, et al. Among authors: kandel es. Expert Opin Ther Targets. 2010 Jul;14(7):703-25. doi: 10.1517/14728222.2010.492779. Expert Opin Ther Targets. 2010. PMID: 20507214 Free PMC article. Review.

5

The response to PAK1 inhibitor IPA3 distinguishes between cancer cells with mutations in BRAF and Ras oncogenes.

Singhal R, Kandel ES. Singhal R, et al. Among authors: kandel es. Oncotarget. 2012 Jul;3(7):700-8. doi: 10.18632/oncotarget.587. Oncotarget. 2012. PMID: 22869096 Free PMC article.

6

Nrf2 amplifies oxidative stress via induction of Klf9.

Zucker SN, Fink EE, Bagati A, Mannava S, Bianchi-Smiraglia A, Bogner PN, Wawrzyniak JA, Foley C, Leonova KI, Grimm MJ, Moparthy K, Ionov Y, Wang J, Liu S, Sexton S, Kandel ES, Bakin AV, Zhang Y, Kaminski N, Segal BH, Nikiforov MA. Zucker SN, et al. Among authors: kandel es. Mol Cell. 2014 Mar 20;53(6):916-928. doi: 10.1016/j.molcel.2014.01.033. Epub 2014 Mar 6. Mol Cell. 2014. PMID: 24613345 Free PMC article.

7

Protein kinase A type II-α regulatory subunit regulates the response of prostate cancer cells to taxane treatment.

Zynda ER, Matveev V, Makhanov M, Chenchik A, Kandel ES. Zynda ER, et al. Among authors: kandel es. Cell Cycle. 2014;13(20):3292-301. doi: 10.4161/15384101.2014.949501. Cell Cycle. 2014. PMID: 25485509 Free PMC article.

8

MicroRNA analysis suggests an additional level of feedback regulation in the NF-κB signaling cascade.

Mechtler P, Singhal R, Kichina JV, Bard JE, Buck MJ, Kandel ES. Mechtler P, et al. Among authors: kandel es. Oncotarget. 2015 Jul 10;6(19):17097-106. doi: 10.18632/oncotarget.4005. Oncotarget. 2015. PMID: 26020802 Free PMC article.

9

An RNA interference screen identifies new avenues for nephroprotection.

Zynda ER, Schott B, Babagana M, Gruener S, Wernher E, Nguyen GD, Ebeling M, Kandel ES. Zynda ER, et al. Among authors: kandel es. Cell Death Differ. 2016 Apr;23(4):608-15. doi: 10.1038/cdd.2015.128. Epub 2015 Nov 13. Cell Death Differ. 2016. PMID: 26564400 Free PMC article.

10

P21-activated kinase 1 regulates resistance to BRAF inhibition in human cancer cells.

Babagana M, Johnson S, Slabodkin H, Bshara W, Morrison C, Kandel ES. Babagana M, et al. Among authors: kandel es. Mol Carcinog. 2017 May;56(5):1515-1525. doi: 10.1002/mc.22611. Epub 2017 Feb 23. Mol Carcinog. 2017. PMID: 28052407 Free PMC article.

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