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Macrophage-Specific NF-κB Activation Dynamics Can Segregate Inflammatory Bowel Disease Patients.
Papoutsopoulou S, Burkitt MD, Bergey F, England H, Hough R, Schmidt L, Spiller DG, White MHR, Paszek P, Jackson DA, Martins Dos Santos VAP, Sellge G, Pritchard DM, Campbell BJ, Müller W, Probert CS. Papoutsopoulou S, et al. Among authors: spiller dg. Front Immunol. 2019 Sep 11;10:2168. doi: 10.3389/fimmu.2019.02168. eCollection 2019. Front Immunol. 2019. PMID: 31572379 Free PMC article. Clinical Trial.
Using systems medicine to identify a therapeutic agent with potential for repurposing in inflammatory bowel disease.
Lloyd K, Papoutsopoulou S, Smith E, Stegmaier P, Bergey F, Morris L, Kittner M, England H, Spiller D, White MHR, Duckworth CA, Campbell BJ, Poroikov V, Martins Dos Santos VAP, Kel A, Muller W, Pritchard DM, Probert C, Burkitt MD; SysmedIBD Consortium. Lloyd K, et al. Dis Model Mech. 2020 Nov 27;13(11):dmm044040. doi: 10.1242/dmm.044040. Dis Model Mech. 2020. PMID: 32958515 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 34005057
Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation.
Bagnall J, Boddington C, England H, Brignall R, Downton P, Alsoufi Z, Boyd J, Rowe W, Bennett A, Walker C, Adamson A, Patel NMX, O'Cualain R, Schmidt L, Spiller DG, Jackson DA, Müller W, Muldoon M, White MRH, Paszek P. Bagnall J, et al. Among authors: spiller dg. Sci Signal. 2018 Jul 24;11(540):eaaf3998. doi: 10.1126/scisignal.aaf3998. Sci Signal. 2018. PMID: 30042130
131 results