Johnson TN - Search Results

1

A Preterm Physiologically Based Pharmacokinetic Model. Part I: Physiological Parameters and Model Building.

Abduljalil K, Pan X, Pansari A, Jamei M, Johnson TN. Abduljalil K, et al. Among authors: johnson tn. Clin Pharmacokinet. 2020 Apr;59(4):485-500. doi: 10.1007/s40262-019-00825-6. Clin Pharmacokinet. 2020. PMID: 31583613

2

Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children.

Johnson TN, Rostami-Hodjegan A, Tucker GT. Johnson TN, et al. Clin Pharmacokinet. 2006;45(9):931-56. doi: 10.2165/00003088-200645090-00005. Clin Pharmacokinet. 2006. PMID: 16928154

3

A semi-mechanistic model to predict the effects of liver cirrhosis on drug clearance.

Johnson TN, Boussery K, Rowland-Yeo K, Tucker GT, Rostami-Hodjegan A. Johnson TN, et al. Clin Pharmacokinet. 2010 Mar;49(3):189-206. doi: 10.2165/11318160-000000000-00000. Clin Pharmacokinet. 2010. PMID: 20170207

4

Resurgence in the use of physiologically based pharmacokinetic models in pediatric clinical pharmacology: parallel shift in incorporating the knowledge of biological elements and increased applicability to drug development and clinical practice.

Johnson TN, Rostami-Hodjegan A. Johnson TN, et al. Paediatr Anaesth. 2011 Mar;21(3):291-301. doi: 10.1111/j.1460-9592.2010.03323.x. Paediatr Anaesth. 2011. PMID: 20497354

5

Application of a systems approach to the bottom-up assessment of pharmacokinetics in obese patients: expected variations in clearance.

Ghobadi C, Johnson TN, Aarabi M, Almond LM, Allabi AC, Rowland-Yeo K, Jamei M, Rostami-Hodjegan A. Ghobadi C, et al. Among authors: johnson tn. Clin Pharmacokinet. 2011 Dec 1;50(12):809-22. doi: 10.2165/11594420-000000000-00000. Clin Pharmacokinet. 2011. PMID: 22087867

6

Physiologically-based pharmacokinetic (PBPK) models for assessing the kinetics of xenobiotics during pregnancy: achievements and shortcomings.

Lu G, Abduljalil K, Jamei M, Johnson TN, Soltani H, Rostami-Hodjegan A. Lu G, et al. Among authors: johnson tn. Curr Drug Metab. 2012 Jul;13(6):695-720. doi: 10.2174/138920012800840374. Curr Drug Metab. 2012. PMID: 22452453 Review.

7

Anatomical, physiological and metabolic changes with gestational age during normal pregnancy: a database for parameters required in physiologically based pharmacokinetic modelling.

Abduljalil K, Furness P, Johnson TN, Rostami-Hodjegan A, Soltani H. Abduljalil K, et al. Among authors: johnson tn. Clin Pharmacokinet. 2012 Jun 1;51(6):365-96. doi: 10.2165/11597440-000000000-00000. Clin Pharmacokinet. 2012. PMID: 22515555

8

A pregnancy physiologically based pharmacokinetic (p-PBPK) model for disposition of drugs metabolized by CYP1A2, CYP2D6 and CYP3A4.

Gaohua L, Abduljalil K, Jamei M, Johnson TN, Rostami-Hodjegan A. Gaohua L, et al. Among authors: johnson tn. Br J Clin Pharmacol. 2012 Nov;74(5):873-85. doi: 10.1111/j.1365-2125.2012.04363.x. Br J Clin Pharmacol. 2012. PMID: 22725721 Free PMC article.

9

Precision criteria to derive sample size when designing pediatric pharmacokinetic studies: which measure of variability should be used?

Salem F, Ogungbenro K, Vajjah P, Johnson TN, Aarons L, Rostami-Hodjegan A. Salem F, et al. Among authors: johnson tn. J Clin Pharmacol. 2014 Mar;54(3):311-7. doi: 10.1002/jcph.206. Epub 2013 Nov 19. J Clin Pharmacol. 2014. PMID: 24122884

10

A re-evaluation and validation of ontogeny functions for cytochrome P450 1A2 and 3A4 based on in vivo data.

Salem F, Johnson TN, Abduljalil K, Tucker GT, Rostami-Hodjegan A. Salem F, et al. Among authors: johnson tn. Clin Pharmacokinet. 2014 Jul;53(7):625-36. doi: 10.1007/s40262-014-0140-7. Clin Pharmacokinet. 2014. PMID: 24671884

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