Debnath A - Search Results

1

Identification of Four Amoebicidal Nontoxic Compounds by a Molecular Docking Screen of Naegleria fowleri Sterol Δ8-Δ7-Isomerase and Phenotypic Assays.

Shi D, Chahal KK, Oto P, Nothias LF, Debnath A, McKerrow JH, Podust LM, Abagyan R. Shi D, et al. Among authors: debnath a. ACS Infect Dis. 2019 Dec 13;5(12):2029-2038. doi: 10.1021/acsinfecdis.9b00227. Epub 2019 Oct 17. ACS Infect Dis. 2019. PMID: 31583882 Free PMC article.

2

Identification of genomic responses to collagen binding by trophozoites of Entamoeba histolytica.

Debnath A, Das P, Sajid M, McKerrow JH. Debnath A, et al. J Infect Dis. 2004 Aug 1;190(3):448-57. doi: 10.1086/422323. Epub 2004 Jul 2. J Infect Dis. 2004. PMID: 15243916

3

A phagocytosis mutant of Entamoeba histolytica is less virulent due to deficient proteinase expression and release.

Hirata KK, Que X, Melendez-Lopez SG, Debnath A, Myers S, Herdman DS, Orozco E, Bhattacharya A, McKerrow JH, Reed SL. Hirata KK, et al. Among authors: debnath a. Exp Parasitol. 2007 Feb;115(2):192-9. doi: 10.1016/j.exppara.2006.08.004. Epub 2006 Sep 20. Exp Parasitol. 2007. PMID: 16987516

4

Transcriptional and secretory responses of Entamoeba histolytica to mucins, epithelial cells and bacteria.

Debnath A, Tashker JS, Sajid M, McKerrow JH. Debnath A, et al. Int J Parasitol. 2007 Jul;37(8-9):897-906. doi: 10.1016/j.ijpara.2007.01.016. Epub 2007 Feb 12. Int J Parasitol. 2007. PMID: 17362964

5

Mining a cathepsin inhibitor library for new antiparasitic drug leads.

Ang KK, Ratnam J, Gut J, Legac J, Hansell E, Mackey ZB, Skrzypczynska KM, Debnath A, Engel JC, Rosenthal PJ, McKerrow JH, Arkin MR, Renslo AR. Ang KK, et al. Among authors: debnath a. PLoS Negl Trop Dis. 2011 May 3;5(5):e1023. doi: 10.1371/journal.pntd.0001023. PLoS Negl Trop Dis. 2011. PMID: 21572521 Free PMC article.

6

A high-throughput drug screen for Entamoeba histolytica identifies a new lead and target.

Debnath A, Parsonage D, Andrade RM, He C, Cobo ER, Hirata K, Chen S, García-Rivera G, Orozco E, Martínez MB, Gunatilleke SS, Barrios AM, Arkin MR, Poole LB, McKerrow JH, Reed SL. Debnath A, et al. Nat Med. 2012 Jun;18(6):956-60. doi: 10.1038/nm.2758. Nat Med. 2012. PMID: 22610278 Free PMC article.

7

Corifungin, a new drug lead against Naegleria, identified from a high-throughput screen.

Debnath A, Tunac JB, Galindo-Gómez S, Silva-Olivares A, Shibayama M, McKerrow JH. Debnath A, et al. Antimicrob Agents Chemother. 2012 Nov;56(11):5450-7. doi: 10.1128/AAC.00643-12. Epub 2012 Aug 6. Antimicrob Agents Chemother. 2012. PMID: 22869574 Free PMC article.

8

A reprofiled drug, auranofin, is effective against metronidazole-resistant Giardia lamblia.

Tejman-Yarden N, Miyamoto Y, Leitsch D, Santini J, Debnath A, Gut J, McKerrow JH, Reed SL, Eckmann L. Tejman-Yarden N, et al. Among authors: debnath a. Antimicrob Agents Chemother. 2013 May;57(5):2029-35. doi: 10.1128/AAC.01675-12. Epub 2013 Feb 12. Antimicrob Agents Chemother. 2013. PMID: 23403423 Free PMC article.

9

In vitro efficacy of corifungin against Acanthamoeba castellanii trophozoites and cysts.

Debnath A, Tunac JB, Silva-Olivares A, Galindo-Gómez S, Shibayama M, McKerrow JH. Debnath A, et al. Antimicrob Agents Chemother. 2014;58(3):1523-8. doi: 10.1128/AAC.02254-13. Epub 2013 Dec 23. Antimicrob Agents Chemother. 2014. PMID: 24366747 Free PMC article.

10

Hsp90 inhibitors as new leads to target parasitic diarrheal diseases.

Debnath A, Shahinas D, Bryant C, Hirata K, Miyamoto Y, Hwang G, Gut J, Renslo AR, Pillai DR, Eckmann L, Reed SL, McKerrow JH. Debnath A, et al. Antimicrob Agents Chemother. 2014 Jul;58(7):4138-44. doi: 10.1128/AAC.02576-14. Epub 2014 May 12. Antimicrob Agents Chemother. 2014. PMID: 24820073 Free PMC article.

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