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Structure-Based Design, Synthesis and Biological Evaluation of Bis-Tetrahydropyran Furan Acetogenin Mimics Targeting the Trypanosomatid F1 Component of ATP Synthase.
Zacharova MK, Tulloch LB, Gould ER, Fraser AL, King EF, Menzies SK, Smith TK, Florence GJ. Zacharova MK, et al. Among authors: florence gj. European J Org Chem. 2019 Sep 1;2019(31-32):5434-5440. doi: 10.1002/ejoc.201900541. Epub 2019 May 29. European J Org Chem. 2019. PMID: 31598093 Free PMC article.
Design and Synthesis of Broad Spectrum Trypanosomatid Selective Inhibitors.
Fraser AL, Menzies SK, King EFB, Tulloch LB, Gould ER, Zacharova MK, Smith TK, Florence GJ. Fraser AL, et al. Among authors: florence gj. ACS Infect Dis. 2018 Apr 13;4(4):560-567. doi: 10.1021/acsinfecdis.7b00187. Epub 2018 Jan 19. ACS Infect Dis. 2018. PMID: 29313667
Synthesis and stereochemical assignment of (+)-chamuvarinin.
Florence GJ, Morris JC, Murray RG, Osler JD, Reddy VR, Smith TK. Florence GJ, et al. Org Lett. 2011 Feb 4;13(3):514-7. doi: 10.1021/ol1028699. Epub 2010 Dec 21. Org Lett. 2011. PMID: 21174397 Free PMC article.
The trypanosome alternative oxidase: a potential drug target?
Menzies SK, Tulloch LB, Florence GJ, Smith TK. Menzies SK, et al. Among authors: florence gj. Parasitology. 2018 Feb;145(2):175-183. doi: 10.1017/S0031182016002109. Epub 2016 Nov 29. Parasitology. 2018. PMID: 27894362 Review.
Direct and indirect approaches to identify drug modes of action.
Tulloch LB, Menzies SK, Coron RP, Roberts MD, Florence GJ, Smith TK. Tulloch LB, et al. Among authors: florence gj. IUBMB Life. 2018 Jan;70(1):9-22. doi: 10.1002/iub.1697. Epub 2017 Dec 6. IUBMB Life. 2018. PMID: 29210173 Free article. Review.
29 results