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Deletion of calcineurin from GFAP-expressing astrocytes impairs excitability of cerebellar and hippocampal neurons through astroglial Na+ /K+ ATPase.
Tapella L, Soda T, Mapelli L, Bortolotto V, Bondi H, Ruffinatti FA, Dematteis G, Stevano A, Dionisi M, Ummarino S, Di Ruscio A, Distasi C, Grilli M, Genazzani AA, D'Angelo E, Moccia F, Lim D. Tapella L, et al. Among authors: dematteis g. Glia. 2020 Mar;68(3):543-560. doi: 10.1002/glia.23737. Epub 2019 Oct 18. Glia. 2020. PMID: 31626368 Free article.
Proteomic analysis links alterations of bioenergetics, mitochondria-ER interactions and proteostasis in hippocampal astrocytes from 3xTg-AD mice.
Dematteis G, Vydmantaitė G, Ruffinatti FA, Chahin M, Farruggio S, Barberis E, Ferrari E, Marengo E, Distasi C, Morkūnienė R, Genazzani AA, Grilli M, Grossini E, Corazzari M, Manfredi M, Lim D, Jekabsone A, Tapella L. Dematteis G, et al. Cell Death Dis. 2020 Aug 18;11(8):645. doi: 10.1038/s41419-020-02911-1. Cell Death Dis. 2020. PMID: 32811809 Free PMC article.
Deletion of calcineurin from astrocytes reproduces proteome signature of Alzheimer's disease and epilepsy and predisposes to seizures.
Tapella L, Dematteis G, Ruffinatti FA, Ponzoni L, Fiordaliso F, Corbelli A, Albanese E, Pistolato B, Pagano J, Barberis E, Marengo E, Balducci C, Forloni G, Verpelli C, Sala C, Distasi C, Sala M, Manfredi M, Genazzani AA, Lim D. Tapella L, et al. Among authors: dematteis g. Cell Calcium. 2021 Dec;100:102480. doi: 10.1016/j.ceca.2021.102480. Epub 2021 Sep 26. Cell Calcium. 2021. PMID: 34607180
Protein synthesis inhibition and loss of homeostatic functions in astrocytes from an Alzheimer's disease mouse model: a role for ER-mitochondria interaction.
Tapella L, Dematteis G, Moro M, Pistolato B, Tonelli E, Vanella VV, Giustina D, La Forgia A, Restelli E, Barberis E, Cali T, Brini M, Villani S, Del Grosso E, Grilli M, Manfredi M, Corazzari M, Grolla AA, Genazzani AA, Lim D. Tapella L, et al. Among authors: dematteis g. Cell Death Dis. 2022 Oct 18;13(10):878. doi: 10.1038/s41419-022-05324-4. Cell Death Dis. 2022. PMID: 36257957 Free PMC article.
25 results