Leake DS - Search Results

1

Cysteamine inhibits lysosomal oxidation of low density lipoprotein in human macrophages and reduces atherosclerosis in mice.

Wen Y, Ahmad F, Mohri Z, Weinberg PD, Leake DS. Wen Y, et al. Among authors: leake ds. Atherosclerosis. 2019 Dec;291:9-18. doi: 10.1016/j.atherosclerosis.2019.09.019. Epub 2019 Sep 26. Atherosclerosis. 2019. PMID: 31629988 Free PMC article.

2

Antioxidants inhibit low density lipoprotein oxidation less at lysosomal pH: A possible explanation as to why the clinical trials of antioxidants might have failed.

Ahmad F, Leake DS. Ahmad F, et al. Among authors: leake ds. Chem Phys Lipids. 2018 Jul;213:13-24. doi: 10.1016/j.chemphyslip.2018.03.001. Epub 2018 Mar 5. Chem Phys Lipids. 2018. PMID: 29518380 Free PMC article.

3

Lysosomal oxidation of LDL alters lysosomal pH, induces senescence, and increases secretion of pro-inflammatory cytokines in human macrophages.

Ahmad F, Leake DS. Ahmad F, et al. Among authors: leake ds. J Lipid Res. 2019 Jan;60(1):98-110. doi: 10.1194/jlr.M088245. Epub 2018 Nov 5. J Lipid Res. 2019. PMID: 30397186 Free PMC article.

4

Cysteamine Decreases Low-Density Lipoprotein Oxidation, Causes Regression of Atherosclerosis, and Improves Liver and Muscle Function in Low-Density Lipoprotein Receptor-Deficient Mice.

Ahmad F, Mitchell RD, Houben T, Palo A, Yadati T, Parnell AJ, Patel K, Shiri-Sverdlov R, Leake DS. Ahmad F, et al. Among authors: leake ds. J Am Heart Assoc. 2021 Sep 21;10(18):e017524. doi: 10.1161/JAHA.120.017524. Epub 2021 Sep 8. J Am Heart Assoc. 2021. PMID: 34493066 Free PMC article.

5

Low density lipoprotein undergoes oxidation within lysosomes in cells.

Wen Y, Leake DS. Wen Y, et al. Among authors: leake ds. Circ Res. 2007 May 11;100(9):1337-43. doi: 10.1161/CIRCRESAHA.107.151704. Epub 2007 Apr 19. Circ Res. 2007. PMID: 17446432

6

The synthetic glycolipid-based TLR4 antagonist FP7 negatively regulates in vitro and in vivo haematopoietic and non-haematopoietic vascular TLR4 signalling.

Palmer C, Peri F, Neumann F, Ahmad F, Leake DS, Pirianov G. Palmer C, et al. Among authors: leake ds. Innate Immun. 2018 Oct;24(7):411-421. doi: 10.1177/1753425918798904. Epub 2018 Sep 12. Innate Immun. 2018. PMID: 30208782 Free PMC article.

7

Oxidation affects the flow-induced aggregation of low density lipoprotein and its inhibition by albumin.

Talbot RM, del Rio JD, Leake DS, Weinberg PD. Talbot RM, et al. Among authors: leake ds. Biochim Biophys Acta. 2003 Oct 20;1634(1-2):24-9. doi: 10.1016/j.bbalip.2003.08.002. Biochim Biophys Acta. 2003. PMID: 14563410

8

Quantitative immunohistochemical detection of oxidized low density lipoprotein in the rabbit arterial wall.

Javed Q, Leake DS, Weinberg PD. Javed Q, et al. Among authors: leake ds. Exp Mol Pathol. 1999 Feb;65(3):121-40. doi: 10.1016/s0014-4800(99)80002-1. Exp Mol Pathol. 1999. PMID: 10234359

9

Mechanisms by which cysteine can inhibit or promote the oxidation of low density lipoprotein by copper.

Patterson RA, Lamb DJ, Leake DS. Patterson RA, et al. Among authors: leake ds. Atherosclerosis. 2003 Jul;169(1):87-94. doi: 10.1016/s0021-9150(03)00154-0. Atherosclerosis. 2003. PMID: 12860254

10

The oxidative modification of low density lipoprotein by human lymphocytes.

Lamb DJ, Wilkins GM, Leake DS. Lamb DJ, et al. Among authors: leake ds. Atherosclerosis. 1992 Feb;92(2-3):187-92. doi: 10.1016/0021-9150(92)90277-n. Atherosclerosis. 1992. PMID: 1632847

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

107 results

Search Page

Filters