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Waking up dormant tumor suppressor genes with zinc fingers, TALEs and the CRISPR/dCas9 system.
Garcia-Bloj B, Moses C, Sgro A, Plani-Lam J, Arooj M, Duffy C, Thiruvengadam S, Sorolla A, Rashwan R, Mancera RL, Leisewitz A, Swift-Scanlan T, Corvalan AH, Blancafort P. Garcia-Bloj B, et al. Among authors: blancafort p. Oncotarget. 2016 Sep 13;7(37):60535-60554. doi: 10.18632/oncotarget.11142. Oncotarget. 2016. PMID: 27528034 Free PMC article.
Tumor penetrating peptides inhibiting MYC as a potent targeted therapeutic strategy for triple-negative breast cancers.
Wang E, Sorolla A, Cunningham PT, Bogdawa HM, Beck S, Golden E, Dewhurst RE, Florez L, Cruickshank MN, Hoffmann K, Hopkins RM, Kim J, Woo AJ, Watt PM, Blancafort P. Wang E, et al. Among authors: blancafort p. Oncogene. 2019 Jan;38(1):140-150. doi: 10.1038/s41388-018-0421-y. Epub 2018 Aug 3. Oncogene. 2019. PMID: 30076412 Free PMC article.
Tumour suppression by targeted intravenous non-viral CRISPRa using dendritic polymers.
Kretzmann JA, Evans CW, Moses C, Sorolla A, Kretzmann AL, Wang E, Ho D, Hackett MJ, Dessauvagie BF, Smith NM, Redfern AD, Waryah C, Norret M, Iyer KS, Blancafort P. Kretzmann JA, et al. Among authors: blancafort p. Chem Sci. 2019 Jun 27;10(33):7718-7727. doi: 10.1039/c9sc01432b. eCollection 2019 Sep 7. Chem Sci. 2019. PMID: 31588320 Free PMC article.
67 results