Hay JL - Search Results

1

Lack of Detection of the Analgesic Properties of PF-05089771, a Selective Na_v 1.7 Inhibitor, Using a Battery of Pain Models in Healthy Subjects.

Siebenga P, van Amerongen G, Hay JL, McDonnell A, Gorman D, Butt R, Groeneveld GJ. Siebenga P, et al. Among authors: hay jl. Clin Transl Sci. 2020 Mar;13(2):318-324. doi: 10.1111/cts.12712. Epub 2019 Nov 12. Clin Transl Sci. 2020. PMID: 31642607 Free PMC article. Clinical Trial.

2

The use of a battery of pain models to detect analgesic properties of compounds: a two-part four-way crossover study.

Okkerse P, van Amerongen G, de Kam ML, Stevens J, Butt RP, Gurrell R, Dahan A, van Gerven JM, Hay JL, Groeneveld GJ. Okkerse P, et al. Among authors: hay jl. Br J Clin Pharmacol. 2017 May;83(5):976-990. doi: 10.1111/bcp.13183. Epub 2017 Jan 9. Br J Clin Pharmacol. 2017. PMID: 27862179 Free PMC article. Clinical Trial.

3

Demonstration of an anti-hyperalgesic effect of a novel pan-Trk inhibitor PF-06273340 in a battery of human evoked pain models.

Loudon P, Siebenga P, Gorman D, Gore K, Dua P, van Amerongen G, Hay JL, Groeneveld GJ, Butt RP. Loudon P, et al. Among authors: hay jl. Br J Clin Pharmacol. 2018 Feb;84(2):301-309. doi: 10.1111/bcp.13448. Epub 2017 Nov 28. Br J Clin Pharmacol. 2018. PMID: 29178434 Free PMC article. Clinical Trial.

4

Reproducibility of a battery of human evoked pain models to detect pharmacological effects of analgesic drugs.

Siebenga PS, van Amerongen G, Okkerse P, Denney WS, Dua P, Butt RP, Hay JL, Groeneveld GJ. Siebenga PS, et al. Among authors: hay jl. Eur J Pain. 2019 Jul;23(6):1129-1140. doi: 10.1002/ejp.1379. Epub 2019 Apr 5. Eur J Pain. 2019. PMID: 30793411 Free PMC article.

5

Analgesic potential of PF-06372865, an α2/α3/α5 subtype-selective GABA_A partial agonist, in humans.

van Amerongen G, Siebenga PS, Gurrell R, Dua P, Whitlock M, Gorman D, Okkerse P, Hay JL, Butt RP, Groeneveld GJ. van Amerongen G, et al. Among authors: hay jl. Br J Anaesth. 2019 Aug;123(2):e194-e203. doi: 10.1016/j.bja.2018.12.006. Epub 2019 Jan 31. Br J Anaesth. 2019. PMID: 30915991 Free PMC article. Clinical Trial.

6

Effect profile of paracetamol, Δ9-THC and promethazine using an evoked pain test battery in healthy subjects.

van Amerongen G, Siebenga P, de Kam ML, Hay JL, Groeneveld GJ. van Amerongen G, et al. Among authors: hay jl. Eur J Pain. 2018 Aug;22(7):1331-1342. doi: 10.1002/ejp.1222. Epub 2018 Apr 25. Eur J Pain. 2018. PMID: 29635857 Clinical Trial.

7

Responsiveness of electrical nociceptive detection thresholds to capsaicin (8 %)-induced changes in nociceptive processing.

Doll RJ, van Amerongen G, Hay JL, Groeneveld GJ, Veltink PH, Buitenweg JR. Doll RJ, et al. Among authors: hay jl. Exp Brain Res. 2016 Sep;234(9):2505-14. doi: 10.1007/s00221-016-4655-z. Epub 2016 May 3. Exp Brain Res. 2016. PMID: 27142052 Free PMC article. Clinical Trial.

8

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery.

Hay JL, Okkerse P, van Amerongen G, Groeneveld GJ. Hay JL, et al. J Vis Exp. 2016 Apr 14;(110):53800. doi: 10.3791/53800. J Vis Exp. 2016. PMID: 27166581 Free PMC article.

9

A literature review on the pharmacological sensitivity of human evoked hyperalgesia pain models.

van Amerongen G, de Boer MW, Groeneveld GJ, Hay JL. van Amerongen G, et al. Among authors: hay jl. Br J Clin Pharmacol. 2016 Oct;82(4):903-22. doi: 10.1111/bcp.13018. Epub 2016 Jul 8. Br J Clin Pharmacol. 2016. PMID: 27203797 Free PMC article. Review.

10

Pharmacokinetics and pharmacodynamics of intrathecally administered Xen2174, a synthetic conopeptide with norepinephrine reuptake inhibitor and analgesic properties.

Okkerse P, Hay JL, Sitsen E, Dahan A, Klaassen E, Houghton W, Groeneveld GJ. Okkerse P, et al. Among authors: hay jl. Br J Clin Pharmacol. 2017 Apr;83(4):751-763. doi: 10.1111/bcp.13176. Epub 2016 Dec 16. Br J Clin Pharmacol. 2017. PMID: 27987228 Free PMC article. Clinical Trial.

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