Sapkota GP - Search Results

1

Pathogenic FAM83G palmoplantar keratoderma mutations inhibit the PAWS1:CK1α association and attenuate Wnt signalling.

Wu KZL, Jones RA, Tachie-Menson T, Macartney TJ, Wood NT, Varghese J, Gourlay R, Soares RF, Smith JC, Sapkota GP. Wu KZL, et al. Among authors: sapkota gp. Wellcome Open Res. 2019 Sep 9;4:133. doi: 10.12688/wellcomeopenres.15403.2. eCollection 2019. Wellcome Open Res. 2019. PMID: 31656861 Free PMC article.

2

Reduction of nitrite to nitric oxide catalyzed by xanthine oxidoreductase.

Godber BL, Doel JJ, Sapkota GP, Blake DR, Stevens CR, Eisenthal R, Harrison R. Godber BL, et al. Among authors: sapkota gp. J Biol Chem. 2000 Mar 17;275(11):7757-63. doi: 10.1074/jbc.275.11.7757. J Biol Chem. 2000. PMID: 10713088 Free article.

3

USP11 augments TGFβ signalling by deubiquitylating ALK5.

Al-Salihi MA, Herhaus L, Macartney T, Sapkota GP. Al-Salihi MA, et al. Among authors: sapkota gp. Open Biol. 2012 Jun;2(6):120063. doi: 10.1098/rsob.120063. Open Biol. 2012. PMID: 22773947 Free PMC article.

4

Protein phosphatase 5 modulates SMAD3 function in the transforming growth factor-β pathway.

Bruce DL, Macartney T, Yong W, Shou W, Sapkota GP. Bruce DL, et al. Among authors: sapkota gp. Cell Signal. 2012 Nov;24(11):1999-2006. doi: 10.1016/j.cellsig.2012.07.003. Epub 2012 Jul 7. Cell Signal. 2012. PMID: 22781750

5

OTUB1 enhances TGFβ signalling by inhibiting the ubiquitylation and degradation of active SMAD2/3.

Herhaus L, Al-Salihi M, Macartney T, Weidlich S, Sapkota GP. Herhaus L, et al. Among authors: sapkota gp. Nat Commun. 2013;4:2519. doi: 10.1038/ncomms3519. Nat Commun. 2013. PMID: 24071738 Free PMC article.

6

Protein associated with SMAD1 (PAWS1/FAM83G) is a substrate for type I bone morphogenetic protein receptors and modulates bone morphogenetic protein signalling.

Vogt J, Dingwell KS, Herhaus L, Gourlay R, Macartney T, Campbell D, Smith JC, Sapkota GP. Vogt J, et al. Among authors: sapkota gp. Open Biol. 2014 Feb 19;4(2):130210. doi: 10.1098/rsob.130210. Open Biol. 2014. PMID: 24554596 Free PMC article.

7

USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling.

Herhaus L, Al-Salihi MA, Dingwell KS, Cummins TD, Wasmus L, Vogt J, Ewan R, Bruce D, Macartney T, Weidlich S, Smith JC, Sapkota GP. Herhaus L, et al. Among authors: sapkota gp. Open Biol. 2014 May;4(5):140065. doi: 10.1098/rsob.140065. Open Biol. 2014. PMID: 24850914 Free PMC article.

8

Casein kinase 2 (CK2) phosphorylates the deubiquitylase OTUB1 at Ser16 to trigger its nuclear localization.

Herhaus L, Perez-Oliva AB, Cozza G, Gourlay R, Weidlich S, Campbell DG, Pinna LA, Sapkota GP. Herhaus L, et al. Among authors: sapkota gp. Sci Signal. 2015 Apr 14;8(372):ra35. doi: 10.1126/scisignal.aaa0441. Sci Signal. 2015. PMID: 25872870 Free PMC article.

9

Rapid generation of endogenously driven transcriptional reporters in cells through CRISPR/Cas9.

Rojas-Fernandez A, Herhaus L, Macartney T, Lachaud C, Hay RT, Sapkota GP. Rojas-Fernandez A, et al. Among authors: sapkota gp. Sci Rep. 2015 Apr 29;5:9811. doi: 10.1038/srep09811. Sci Rep. 2015. PMID: 25922883 Free PMC article.

10

An affinity-directed protein missile system for targeted proteolysis.

Fulcher LJ, Macartney T, Bozatzi P, Hornberger A, Rojas-Fernandez A, Sapkota GP. Fulcher LJ, et al. Among authors: sapkota gp. Open Biol. 2016 Oct;6(10):160255. doi: 10.1098/rsob.160255. Open Biol. 2016. PMID: 27784791 Free PMC article.

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