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CRISPR: A Screener's Guide.
le Sage C, Lawo S, Cross BCS. le Sage C, et al. SLAS Discov. 2020 Mar;25(3):233-240. doi: 10.1177/2472555219883621. Epub 2019 Oct 29. SLAS Discov. 2020. PMID: 31658850 Free PMC article.
A Flexible, Pooled CRISPR Library for Drug Development Screens.
Blanck M, Budnik-Zawilska MB, Lenger SR, McGonigle JE, Martin GRA, le Sage C, Lawo S, Pemberton HN, Tiwana GS, Sorrell DA, Cross BCS. Blanck M, et al. Among authors: le sage c. CRISPR J. 2020 Jun;3(3):211-222. doi: 10.1089/crispr.2019.0066. CRISPR J. 2020. PMID: 33054419 Free PMC article.
Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumors.
Bellail AC, Jin HR, Lo HY, Jung SH, Hamdouchi C, Kim D, Higgins RK, Blanck M, le Sage C, Cross BCS, Li J, Mosley AL, Wijeratne AB, Jiang W, Ghosh M, Zhao YQ, Hauck PM, Shekhar A, Hao C. Bellail AC, et al. Among authors: le sage c. Sci Transl Med. 2021 Oct 13;13(615):eabh1486. doi: 10.1126/scitranslmed.abh1486. Epub 2021 Oct 13. Sci Transl Med. 2021. PMID: 34644148 Free PMC article.
Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites.
Brown JS, Lukashchuk N, Sczaniecka-Clift M, Britton S, le Sage C, Calsou P, Beli P, Galanty Y, Jackson SP. Brown JS, et al. Among authors: le sage c. Cell Rep. 2015 May 5;11(5):704-14. doi: 10.1016/j.celrep.2015.03.058. Epub 2015 Apr 23. Cell Rep. 2015. PMID: 25921528 Free PMC article.
Synthetic lethality between PAXX and XLF in mammalian development.
Balmus G, Barros AC, Wijnhoven PW, Lescale C, Hasse HL, Boroviak K, le Sage C, Doe B, Speak AO, Galli A, Jacobsen M, Deriano L, Adams DJ, Blackford AN, Jackson SP. Balmus G, et al. Among authors: le sage c. Genes Dev. 2016 Oct 1;30(19):2152-2157. doi: 10.1101/gad.290510.116. Genes Dev. 2016. PMID: 27798842 Free PMC article.
32 results