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Natural human genetic variation determines basal and inducible expression of PM20D1, an obesity-associated gene.
Benson KK, Hu W, Weller AH, Bennett AH, Chen ER, Khetarpal SA, Yoshino S, Bone WP, Wang L, Rabinowitz JD, Voight BF, Soccio RE. Benson KK, et al. Among authors: rabinowitz jd. Proc Natl Acad Sci U S A. 2019 Nov 12;116(46):23232-23242. doi: 10.1073/pnas.1913199116. Epub 2019 Oct 28. Proc Natl Acad Sci U S A. 2019. PMID: 31659023 Free PMC article.
Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma.
Ducker GS, Ghergurovich JM, Mainolfi N, Suri V, Jeong SK, Hsin-Jung Li S, Friedman A, Manfredi MG, Gitai Z, Kim H, Rabinowitz JD. Ducker GS, et al. Among authors: rabinowitz jd. Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):11404-11409. doi: 10.1073/pnas.1706617114. Epub 2017 Oct 9. Proc Natl Acad Sci U S A. 2017. PMID: 29073064 Free PMC article.
Defective respiration and one-carbon metabolism contribute to impaired naïve T cell activation in aged mice.
Ron-Harel N, Notarangelo G, Ghergurovich JM, Paulo JA, Sage PT, Santos D, Satterstrom FK, Gygi SP, Rabinowitz JD, Sharpe AH, Haigis MC. Ron-Harel N, et al. Among authors: rabinowitz jd. Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):13347-13352. doi: 10.1073/pnas.1804149115. Epub 2018 Dec 10. Proc Natl Acad Sci U S A. 2018. PMID: 30530686 Free PMC article.
308 results