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4'-Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN.
Jeong SY, Hogarth P, Placzek A, Gregory AM, Fox R, Zhen D, Hamada J, van der Zwaag M, Lambrechts R, Jin H, Nilsen A, Cobb J, Pham T, Gray N, Ralle M, Duffy M, Schwanemann L, Rai P, Freed A, Wakeman K, Woltjer RL, Sibon OC, Hayflick SJ. Jeong SY, et al. Among authors: jin h. EMBO Mol Med. 2019 Dec;11(12):e10489. doi: 10.15252/emmm.201910489. Epub 2019 Oct 29. EMBO Mol Med. 2019. PMID: 31660701 Free PMC article.
Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells.
Jin H, Ladd NA, Peev AM, Swarbrick GM, Cansler M, Null M, Boughter CT, McMurtrey C, Nilsen A, Dobos KM, Hildebrand WH, Lewinsohn DA, Adams EJ, Lewinsohn DM, Harriff MJ. Jin H, et al. Sci Rep. 2022 Dec 29;12(1):22539. doi: 10.1038/s41598-022-26259-y. Sci Rep. 2022. PMID: 36581641 Free PMC article.
A New Scalable Synthesis of ELQ-300, ELQ-316, and other Antiparasitic Quinolones.
Pou S, Dodean RA, Frueh L, Liebman KM, Gallagher RT, Jin H, Jacobs RT, Nilsen A, Stuart DR, Doggett JS, Riscoe MK, Winter RW. Pou S, et al. Among authors: jin h. Org Process Res Dev. 2021 Aug 20;25(8):1841-1852. doi: 10.1021/acs.oprd.1c00099. Epub 2021 Aug 4. Org Process Res Dev. 2021. PMID: 35110959 Free PMC article.
Characterization of a Novel Compound That Stimulates STING-Mediated Innate Immune Activity in an Allele-Specific Manner.
Abraham J, Botto S, Mizuno N, Pryke K, Gall B, Boehm D, Sali TM, Jin H, Nilsen A, Gough M, Baird J, Chakhtoura M, Subra C, Trautmann L, Haddad EK, DeFilippis VR. Abraham J, et al. Among authors: jin h. Front Immunol. 2020 Jul 8;11:1430. doi: 10.3389/fimmu.2020.01430. eCollection 2020. Front Immunol. 2020. PMID: 32733475 Free PMC article.
Therapeutics That Promote Sympathetic Reinnervation Modulate the Inflammatory Response After Myocardial Infarction.
Sepe JJ, Gardner RT, Blake MR, Brooks DM, Staffenson MA, Betts CB, Sivagnanam S, Larson W, Kumar S, Bayles RG, Jin H, Cohen MS, Coussens LM, Habecker BA. Sepe JJ, et al. Among authors: jin h. JACC Basic Transl Sci. 2022 Aug 24;7(9):915-930. doi: 10.1016/j.jacbts.2022.04.009. eCollection 2022 Sep. JACC Basic Transl Sci. 2022. PMID: 36317132 Free PMC article.
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