Gaggar A - Search Results

1

Neutrophil-targeted, protease-activated pulmonary drug delivery blocks airway and systemic inflammation.

Mejías JC, Forrest OA, Margaroli C, Frey Rubio DA, Viera L, Li J, Xu X, Gaggar A, Tirouvanziam R, Roy K. Mejías JC, et al. Among authors: gaggar a. JCI Insight. 2019 Dec 5;4(23):e131468. doi: 10.1172/jci.insight.131468. JCI Insight. 2019. PMID: 31661469 Free PMC article.

2

Neutrophils contain prolyl endopeptidase and generate the chemotactic peptide, PGP, from collagen.

O'Reilly PJ, Hardison MT, Jackson PL, Xu X, Snelgrove RJ, Gaggar A, Galin FS, Blalock JE. O'Reilly PJ, et al. Among authors: gaggar a. J Neuroimmunol. 2009 Dec 10;217(1-2):51-4. doi: 10.1016/j.jneuroim.2009.09.020. Epub 2009 Oct 28. J Neuroimmunol. 2009. PMID: 19875179 Free PMC article.

3

Human neutrophil elastase-mediated cleavage sites of MMP-9 and TIMP-1: implications to cystic fibrosis proteolytic dysfunction.

Jackson PL, Xu X, Wilson L, Weathington NM, Clancy JP, Blalock JE, Gaggar A. Jackson PL, et al. Among authors: gaggar a. Mol Med. 2010 May-Jun;16(5-6):159-66. doi: 10.2119/molmed.2009.00109. Epub 2010 Jan 22. Mol Med. 2010. PMID: 20111696 Free PMC article.

4

A self-propagating matrix metalloprotease-9 (MMP-9) dependent cycle of chronic neutrophilic inflammation.

Xu X, Jackson PL, Tanner S, Hardison MT, Abdul Roda M, Blalock JE, Gaggar A. Xu X, et al. Among authors: gaggar a. PLoS One. 2011 Jan 13;6(1):e15781. doi: 10.1371/journal.pone.0015781. PLoS One. 2011. PMID: 21249198 Free PMC article.

5

Free radical-producing myeloid-derived regulatory cells: potent activators and suppressors of lung inflammation and airway hyperresponsiveness.

Deshane J, Zmijewski JW, Luther R, Gaggar A, Deshane R, Lai JF, Xu X, Spell M, Estell K, Weaver CT, Abraham E, Schwiebert LM, Chaplin DD. Deshane J, et al. Among authors: gaggar a. Mucosal Immunol. 2011 Sep;4(5):503-18. doi: 10.1038/mi.2011.16. Epub 2011 Apr 6. Mucosal Immunol. 2011. PMID: 21471960 Free PMC article.

6

Anti-inflammatory mechanisms of apolipoprotein A-I mimetic peptide in acute respiratory distress syndrome secondary to sepsis.

Sharifov OF, Xu X, Gaggar A, Grizzle WE, Mishra VK, Honavar J, Litovsky SH, Palgunachari MN, White CR, Anantharamaiah GM, Gupta H. Sharifov OF, et al. Among authors: gaggar a. PLoS One. 2013 May 14;8(5):e64486. doi: 10.1371/journal.pone.0064486. Print 2013. PLoS One. 2013. PMID: 23691230 Free PMC article.

7

Pulmonary matrix metalloproteinase-9 activity in mechanically ventilated children with respiratory syncytial virus.

Kong MY, Clancy JP, Peng N, Li Y, Szul TJ, Xu X, Oster R, Sullender W, Ambalavanan N, Blalock JE, Gaggar A. Kong MY, et al. Among authors: gaggar a. Eur Respir J. 2014 Apr;43(4):1086-96. doi: 10.1183/09031936.00105613. Epub 2013 Dec 5. Eur Respir J. 2014. PMID: 24311764 Free PMC article.

8

L-4F inhibits lipopolysaccharide-mediated activation of primary human neutrophils.

Sharifov OF, Xu X, Gaggar A, Tabengwa EM, White CR, Palgunachari MN, Anantharamaiah GM, Gupta H. Sharifov OF, et al. Among authors: gaggar a. Inflammation. 2014 Oct;37(5):1401-12. doi: 10.1007/s10753-014-9864-7. Inflammation. 2014. PMID: 24647607 Free PMC article.

9

Alterations in blood leukocytes of G551D-bearing cystic fibrosis patients undergoing treatment with ivacaftor.

Bratcher PE, Rowe SM, Reeves G, Roberts T, Szul T, Harris WT, Tirouvanziam R, Gaggar A. Bratcher PE, et al. Among authors: gaggar a. J Cyst Fibros. 2016 Jan;15(1):67-73. doi: 10.1016/j.jcf.2015.02.010. Epub 2015 Mar 11. J Cyst Fibros. 2016. PMID: 25769931 Free PMC article.

10

A Randomized, Placebo-controlled Trial of Roflumilast. Effect on Proline-Glycine-Proline and Neutrophilic Inflammation in Chronic Obstructive Pulmonary Disease.

Wells JM, Jackson PL, Viera L, Bhatt SP, Gautney J, Handley G, King RW, Xu X, Gaggar A, Bailey WC, Dransfield MT, Blalock JE. Wells JM, et al. Among authors: gaggar a. Am J Respir Crit Care Med. 2015 Oct 15;192(8):934-42. doi: 10.1164/rccm.201503-0543OC. Am J Respir Crit Care Med. 2015. PMID: 26151090 Free PMC article. Clinical Trial.

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