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The combination of inhibitors of FGF/MEK/Erk and GSK3β signaling increases the number of OCT3/4- and NANOG-positive cells in the human inner cell mass, but does not improve stem cell derivation.
Van der Jeught M, O'Leary T, Ghimire S, Lierman S, Duggal G, Versieren K, Deforce D, Chuva de Sousa Lopes S, Heindryckx B, De Sutter P. Van der Jeught M, et al. Among authors: heindryckx b. Stem Cells Dev. 2013 Jan 15;22(2):296-306. doi: 10.1089/scd.2012.0256. Epub 2012 Aug 6. Stem Cells Dev. 2013. PMID: 22784186 Free PMC article.
Influence of activin A supplementation during human embryonic stem cell derivation on germ cell differentiation potential.
Duggal G, Heindryckx B, Warrier S, O'Leary T, Van der Jeught M, Lierman S, Vossaert L, Deroo T, Deforce D, Chuva de Sousa Lopes SM, De Sutter P. Duggal G, et al. Among authors: heindryckx b. Stem Cells Dev. 2013 Dec 1;22(23):3141-55. doi: 10.1089/scd.2013.0024. Epub 2013 Aug 14. Stem Cells Dev. 2013. PMID: 23829223 Free PMC article.
Detailed method description for noninvasive monitoring of differentiation status of human embryonic stem cells.
Scheerlinck E, Van Steendam K, Vandewoestyne M, Lepez T, Gobin V, Meert P, Vossaert L, Van Nieuwerburgh F, Van Soom A, Peelman L, Heindryckx B, De Sutter P, Dhaenens M, Deforce D. Scheerlinck E, et al. Among authors: heindryckx b. Anal Biochem. 2014 Sep 15;461:60-6. doi: 10.1016/j.ab.2014.05.026. Epub 2014 Jun 5. Anal Biochem. 2014. PMID: 24909445 Free article.
Alternative Routes to Induce Naïve Pluripotency in Human Embryonic Stem Cells.
Duggal G, Warrier S, Ghimire S, Broekaert D, Van der Jeught M, Lierman S, Deroo T, Peelman L, Van Soom A, Cornelissen R, Menten B, Mestdagh P, Vandesompele J, Roost M, Slieker RC, Heijmans BT, Deforce D, De Sutter P, De Sousa Lopes SC, Heindryckx B. Duggal G, et al. Among authors: heindryckx b. Stem Cells. 2015 Sep;33(9):2686-98. doi: 10.1002/stem.2071. Epub 2015 Jun 24. Stem Cells. 2015. PMID: 26108678
127 results