Lu B - Search Results

1

Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds.

Li Z, Wang C, Wang Z, Zhu C, Li J, Sha T, Ma L, Gao C, Yang Y, Sun Y, Wang J, Sun X, Lu C, Difiglia M, Mei Y, Ding C, Luo S, Dang Y, Ding Y, Fei Y, Lu B. Li Z, et al. Among authors: lu b, lu c. Nature. 2019 Nov;575(7781):203-209. doi: 10.1038/s41586-019-1722-1. Epub 2019 Oct 30. Nature. 2019. PMID: 31666698

2

Inhibition of Na+ channel currents in rat myoblasts by 4-aminopyridine.

Lu BX, Liu LY, Liao L, Zhang ZH, Mei YA. Lu BX, et al. Toxicol Appl Pharmacol. 2005 Sep 15;207(3):275-82. doi: 10.1016/j.taap.2005.01.009. Toxicol Appl Pharmacol. 2005. PMID: 16129120

3

A novel human embryonic stem cell-derived Huntington's disease neuronal model exhibits mutant huntingtin (mHTT) aggregates and soluble mHTT-dependent neurodegeneration.

Lu B, Palacino J. Lu B, et al. FASEB J. 2013 May;27(5):1820-9. doi: 10.1096/fj.12-219220. Epub 2013 Jan 16. FASEB J. 2013. PMID: 23325320

4

Identification of NUB1 as a suppressor of mutant Huntington toxicity via enhanced protein clearance.

Lu B, Al-Ramahi I, Valencia A, Wang Q, Berenshteyn F, Yang H, Gallego-Flores T, Ichcho S, Lacoste A, Hild M, Difiglia M, Botas J, Palacino J. Lu B, et al. Nat Neurosci. 2013 May;16(5):562-70. doi: 10.1038/nn.3367. Epub 2013 Mar 24. Nat Neurosci. 2013. PMID: 23525043

5

Drugging unconventional targets: insights from Huntington's disease.

Yu S, Liang Y, Palacino J, Difiglia M, Lu B. Yu S, et al. Among authors: lu b. Trends Pharmacol Sci. 2014 Feb;35(2):53-62. doi: 10.1016/j.tips.2013.12.001. Epub 2014 Jan 2. Trends Pharmacol Sci. 2014. PMID: 24388390 Review.

6

TR-FRET assays of Huntingtin protein fragments reveal temperature and polyQ length-dependent conformational changes.

Cui X, Liang Q, Liang Y, Lu M, Ding Y, Lu B. Cui X, et al. Among authors: lu m, lu b. Sci Rep. 2014 Jul 7;4:5601. doi: 10.1038/srep05601. Sci Rep. 2014. PMID: 24998512 Free PMC article.

7

A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity.

Yao Y, Cui X, Al-Ramahi I, Sun X, Li B, Hou J, Difiglia M, Palacino J, Wu ZY, Ma L, Botas J, Lu B. Yao Y, et al. Among authors: lu b. Elife. 2015 Mar 4;4:e05449. doi: 10.7554/eLife.05449. Elife. 2015. PMID: 25738228 Free PMC article.

8

A high-throughput-compatible assay to measure the degradation of endogenous Huntingtin proteins.

Wu P, Lu MX, Cui XT, Yang HQ, Yu SL, Zhu JB, Sun XL, Lu B. Wu P, et al. Among authors: lu mx, lu b. Acta Pharmacol Sin. 2016 Sep;37(10):1307-1314. doi: 10.1038/aps.2016.31. Epub 2016 Jun 6. Acta Pharmacol Sin. 2016. PMID: 27264314 Free PMC article.

9

Effects of Exogenous NUB1 Expression in the Striatum of HDQ175/Q7 Mice.

Vodicka P, Chase K, Iuliano M, Valentine DT, Sapp E, Lu B, Kegel-Gleason KB, Sena-Esteves M, Aronin N, DiFiglia M. Vodicka P, et al. Among authors: lu b. J Huntingtons Dis. 2016 Jun 13;5(2):163-74. doi: 10.3233/JHD-160195. J Huntingtons Dis. 2016. PMID: 27314618

10

AlphaLISA detection of alpha-synuclein in the cerebrospinal fluid and its potential application in Parkinson's disease diagnosis.

Zhao H, Zhao J, Hou J, Wang S, Ding Y, Lu B, Wang J. Zhao H, et al. Among authors: lu b. Protein Cell. 2017 Sep;8(9):696-700. doi: 10.1007/s13238-017-0424-4. Protein Cell. 2017. PMID: 28555377 Free PMC article. No abstract available.

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