Milligan P - Search Results

1

Open Systems Pharmacology Community-An Open Access, Open Source, Open Science Approach to Modeling and Simulation in Pharmaceutical Sciences.

Lippert J, Burghaus R, Edginton A, Frechen S, Karlsson M, Kovar A, Lehr T, Milligan P, Nock V, Ramusovic S, Riggs M, Schaller S, Schlender J, Schmidt S, Sevestre M, Sjögren E, Solodenko J, Staab A, Teutonico D. Lippert J, et al. Among authors: milligan p. CPT Pharmacometrics Syst Pharmacol. 2019 Dec;8(12):878-882. doi: 10.1002/psp4.12473. Epub 2019 Nov 12. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 31671256 Free PMC article. Review. No abstract available.

2

Good Practices in Model-Informed Drug Discovery and Development: Practice, Application, and Documentation.

EFPIA MID3 Workgroup; Marshall SF, Burghaus R, Cosson V, Cheung SY, Chenel M, DellaPasqua O, Frey N, Hamrén B, Harnisch L, Ivanow F, Kerbusch T, Lippert J, Milligan PA, Rohou S, Staab A, Steimer JL, Tornøe C, Visser SA. EFPIA MID3 Workgroup, et al. Among authors: milligan pa. CPT Pharmacometrics Syst Pharmacol. 2016 Mar;5(3):93-122. doi: 10.1002/psp4.12049. Epub 2016 Mar 14. CPT Pharmacometrics Syst Pharmacol. 2016. PMID: 27069774 Free PMC article.

3

PKPD Modeling of Predictors for Adverse Effects and Overall Survival in Sunitinib-Treated Patients With GIST.

Hansson EK, Ma G, Amantea MA, French J, Milligan PA, Friberg LE, Karlsson MO. Hansson EK, et al. Among authors: milligan pa. CPT Pharmacometrics Syst Pharmacol. 2013 Dec 4;2(12):e85. doi: 10.1038/psp.2013.62. CPT Pharmacometrics Syst Pharmacol. 2013. PMID: 24304978 Free PMC article.

4

PKPD Modeling of VEGF, sVEGFR-2, sVEGFR-3, and sKIT as Predictors of Tumor Dynamics and Overall Survival Following Sunitinib Treatment in GIST.

Hansson EK, Amantea MA, Westwood P, Milligan PA, Houk BE, French J, Karlsson MO, Friberg LE. Hansson EK, et al. Among authors: milligan pa. CPT Pharmacometrics Syst Pharmacol. 2013 Nov 20;2(11):e84. doi: 10.1038/psp.2013.61. CPT Pharmacometrics Syst Pharmacol. 2013. PMID: 24257372 Free PMC article.

5

Assessment of the relative in vivo potency of the hydroxylated metabolite of darifenacin in its ability to decrease salivary flow using pooled population pharmacokinetic-pharmacodynamic data.

Kerbusch T, Milligan PA, Karlsson MO. Kerbusch T, et al. Br J Clin Pharmacol. 2004 Feb;57(2):170-80. doi: 10.1046/j.1365-2125.2003.01988.x. Br J Clin Pharmacol. 2004. PMID: 14748816 Free PMC article.

6

The Role of Modeling and Simulation in Development and Registration of Medicinal Products: Output From the EFPIA/EMA Modeling and Simulation Workshop.

Manolis E, Rohou S, Hemmings R, Salmonson T, Karlsson M, Milligan PA. Manolis E, et al. Among authors: milligan pa. CPT Pharmacometrics Syst Pharmacol. 2013 Feb 27;2(2):e31. doi: 10.1038/psp.2013.7. CPT Pharmacometrics Syst Pharmacol. 2013. PMID: 23835942 Free PMC article.

7

Population pharmacokinetic analysis of voriconazole plasma concentration data from pediatric studies.

Karlsson MO, Lutsar I, Milligan PA. Karlsson MO, et al. Antimicrob Agents Chemother. 2009 Mar;53(3):935-44. doi: 10.1128/AAC.00751-08. Epub 2008 Dec 15. Antimicrob Agents Chemother. 2009. PMID: 19075073 Free PMC article.

8

Models for time-varying covariates in population pharmacokinetic-pharmacodynamic analysis.

Wählby U, Thomson AH, Milligan PA, Karlsson MO. Wählby U, et al. Br J Clin Pharmacol. 2004 Oct;58(4):367-77. doi: 10.1111/j.1365-2125.2004.02170.x. Br J Clin Pharmacol. 2004. PMID: 15373929 Free PMC article.

9

A population pharmacokinetic analysis of sildenafil citrate in patients with erectile dysfunction.

Milligan PA, Marshall SF, Karlsson MO. Milligan PA, et al. Br J Clin Pharmacol. 2002;53 Suppl 1(Suppl 1):45S-52S. doi: 10.1046/j.0306-5251.2001.00032.x. Br J Clin Pharmacol. 2002. PMID: 11879259 Free PMC article. Clinical Trial.

10

Population pharmacokinetic modelling of darifenacin and its hydroxylated metabolite using pooled data, incorporating saturable first-pass metabolism, CYP2D6 genotype and formulation-dependent bioavailability.

Kerbusch T, Wählby U, Milligan PA, Karlsson MO. Kerbusch T, et al. Br J Clin Pharmacol. 2003 Dec;56(6):639-52. doi: 10.1046/j.1365-2125.2003.01967.x. Br J Clin Pharmacol. 2003. PMID: 14616424 Free PMC article.

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