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Selective activity over a constitutively active RET-variant of the oral multikinase inhibitor dovitinib: results of the CNIO-BR002 phase I-trial.
Quintela-Fandino M, Bueno MJ, Lombardia L, Gil M, Gonzalez-Martin A, Marquez R, Bratos R, Guerra J, Tan E, Lopez A, Colomer R, Salazar R. Quintela-Fandino M, et al. Mol Oncol. 2014 Dec;8(8):1719-28. doi: 10.1016/j.molonc.2014.07.005. Epub 2014 Jul 17. Mol Oncol. 2014. PMID: 25103625 Free PMC article. Clinical Trial.
Targeting Tumor Mitochondrial Metabolism Overcomes Resistance to Antiangiogenics.
Navarro P, Bueno MJ, Zagorac I, Mondejar T, Sanchez J, Mourón S, Muñoz J, Gómez-López G, Jimenez-Renard V, Mulero F, Chandel NS, Quintela-Fandino M. Navarro P, et al. Cell Rep. 2016 Jun 21;15(12):2705-18. doi: 10.1016/j.celrep.2016.05.052. Epub 2016 Jun 9. Cell Rep. 2016. PMID: 27292634 Free article.
In vivo phosphoproteomics reveals kinase activity profiles that predict treatment outcome in triple-negative breast cancer.
Zagorac I, Fernandez-Gaitero S, Penning R, Post H, Bueno MJ, Mouron S, Manso L, Morente MM, Alonso S, Serra V, Muñoz J, Gómez-López G, Lopez-Acosta JF, Jimenez-Renard V, Gris-Oliver A, Al-Shahrour F, Piñeiro-Yañez E, Montoya-Suarez JL, Apala JV, Moreno-Torres A, Colomer R, Dopazo A, Heck AJR, Altelaar M, Quintela-Fandino M. Zagorac I, et al. Nat Commun. 2018 Aug 29;9(1):3501. doi: 10.1038/s41467-018-05742-z. Nat Commun. 2018. PMID: 30158526 Free PMC article.
58 results