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The impact of proinflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes.
Ramos-Rodríguez M, Raurell-Vila H, Colli ML, Alvelos MI, Subirana-Granés M, Juan-Mateu J, Norris R, Turatsinze JV, Nakayasu ES, Webb-Robertson BM, Inshaw JRJ, Marchetti P, Piemonti L, Esteller M, Todd JA, Metz TO, Eizirik DL, Pasquali L. Ramos-Rodríguez M, et al. Nat Genet. 2019 Nov;51(11):1588-1595. doi: 10.1038/s41588-019-0524-6. Epub 2019 Nov 1. Nat Genet. 2019. PMID: 31676868 Free PMC article.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling.
Burnum-Johnson KE, Kyle JE, Eisfeld AJ, Casey CP, Stratton KG, Gonzalez JF, Habyarimana F, Negretti NM, Sims AC, Chauhan S, Thackray LB, Halfmann PJ, Walters KB, Kim YM, Zink EM, Nicora CD, Weitz KK, Webb-Robertson BM, Nakayasu ES, Ahmer B, Konkel ME, Motin V, Baric RS, Diamond MS, Kawaoka Y, Waters KM, Smith RD, Metz TO. Burnum-Johnson KE, et al. Analyst. 2017 Jan 26;142(3):442-448. doi: 10.1039/c6an02486f. Analyst. 2017. PMID: 28091625 Free PMC article.
P-Mart: Interactive Analysis of Ion Abundance Global Proteomics Data.
Bramer LM, Stratton KG, White AM, Bleeker AH, Kobold MA, Waters KM, Metz TO, Rodland KD, Webb-Robertson BM. Bramer LM, et al. J Proteome Res. 2019 Mar 1;18(3):1426-1432. doi: 10.1021/acs.jproteome.8b00840. Epub 2019 Feb 6. J Proteome Res. 2019. PMID: 30667224 Free PMC article.
Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention.
Nakayasu ES, Syed F, Tersey SA, Gritsenko MA, Mitchell HD, Chan CY, Dirice E, Turatsinze JV, Cui Y, Kulkarni RN, Eizirik DL, Qian WJ, Webb-Robertson BM, Evans-Molina C, Mirmira RG, Metz TO. Nakayasu ES, et al. Cell Metab. 2020 Feb 4;31(2):363-374.e6. doi: 10.1016/j.cmet.2019.12.005. Epub 2020 Jan 9. Cell Metab. 2020. PMID: 31928885 Free PMC article.
An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells.
Colli ML, Ramos-Rodríguez M, Nakayasu ES, Alvelos MI, Lopes M, Hill JLE, Turatsinze JV, Coomans de Brachène A, Russell MA, Raurell-Vila H, Castela A, Juan-Mateu J, Webb-Robertson BM, Krogvold L, Dahl-Jorgensen K, Marselli L, Marchetti P, Richardson SJ, Morgan NG, Metz TO, Pasquali L, Eizirik DL. Colli ML, et al. Nat Commun. 2020 May 22;11(1):2584. doi: 10.1038/s41467-020-16327-0. Nat Commun. 2020. PMID: 32444635 Free PMC article.
Tutorial: best practices and considerations for mass-spectrometry-based protein biomarker discovery and validation.
Nakayasu ES, Gritsenko M, Piehowski PD, Gao Y, Orton DJ, Schepmoes AA, Fillmore TL, Frohnert BI, Rewers M, Krischer JP, Ansong C, Suchy-Dicey AM, Evans-Molina C, Qian WJ, Webb-Robertson BM, Metz TO. Nakayasu ES, et al. Nat Protoc. 2021 Aug;16(8):3737-3760. doi: 10.1038/s41596-021-00566-6. Epub 2021 Jul 9. Nat Protoc. 2021. PMID: 34244696 Free PMC article. Review.
Interrogating the role of the milk microbiome in mastitis in the multi-omics era.
Couvillion SP, Mostoller KE, Williams JE, Pace RM, Stohel IL, Peterson HK, Nicora CD, Nakayasu ES, Webb-Robertson BM, McGuire MA, McGuire MK, Metz TO. Couvillion SP, et al. Front Microbiol. 2023 Feb 2;14:1105675. doi: 10.3389/fmicb.2023.1105675. eCollection 2023. Front Microbiol. 2023. PMID: 36819069 Free PMC article. Review.
Plasma protein biomarkers predict the development of persistent autoantibodies and type 1 diabetes 6 months prior to the onset of autoimmunity.
Nakayasu ES, Bramer LM, Ansong C, Schepmoes AA, Fillmore TL, Gritsenko MA, Clauss TR, Gao Y, Piehowski PD, Stanfill BA, Engel DW, Orton DJ, Moore RJ, Qian WJ, Sechi S, Frohnert BI, Toppari J, Ziegler AG, Lernmark Å, Hagopian W, Akolkar B, Smith RD, Rewers MJ, Webb-Robertson BM, Metz TO; TEDDY Study Group. Nakayasu ES, et al. Cell Rep Med. 2023 Jul 18;4(7):101093. doi: 10.1016/j.xcrm.2023.101093. Epub 2023 Jun 29. Cell Rep Med. 2023. PMID: 37390828 Free PMC article.
84 results