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Potentiation of NETs release is novel characteristic of TREM-1 activation and the pharmacological inhibition of TREM-1 could prevent from the deleterious consequences of NETs release in sepsis.
Boufenzer A, Carrasco K, Jolly L, Brustolin B, Di-Pillo E, Derive M, Gibot S. Boufenzer A, et al. Among authors: brustolin b. Cell Mol Immunol. 2021 Feb;18(2):452-460. doi: 10.1038/s41423-020-00591-7. Epub 2021 Jan 8. Cell Mol Immunol. 2021. PMID: 33420354 Free PMC article.