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Adult Conditional Knockout of PGC-1α Leads to Loss of Dopamine Neurons.
Jiang H, Kang SU, Zhang S, Karuppagounder S, Xu J, Lee YK, Kang BG, Lee Y, Zhang J, Pletnikova O, Troncoso JC, Pirooznia S, Andrabi SA, Dawson VL, Dawson TM. Jiang H, et al. eNeuro. 2016 Sep 2;3(4):ENEURO.0183-16.2016. doi: 10.1523/ENEURO.0183-16.2016. eCollection 2016 Jul-Aug. eNeuro. 2016. PMID: 27622213 Free PMC article.
A high-affinity cocaine binding site associated with the brain acid soluble protein 1.
Harraz MM, Malla AP, Semenza ER, Shishikura M, Singh M, Hwang Y, Kang IG, Song YJ, Snowman AM, Cortés P, Karuppagounder SS, Dawson TM, Dawson VL, Snyder SH. Harraz MM, et al. Among authors: karuppagounder ss. Proc Natl Acad Sci U S A. 2022 Apr 19;119(16):e2200545119. doi: 10.1073/pnas.2200545119. Epub 2022 Apr 11. Proc Natl Acad Sci U S A. 2022. PMID: 35412917 Free PMC article.
Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice.
Xiong Y, Neifert S, Karuppagounder SS, Liu Q, Stankowski JN, Lee BD, Ko HS, Lee Y, Grima JC, Mao X, Jiang H, Kang SU, Swing DA, Iacovitti L, Tessarollo L, Dawson TM, Dawson VL. Xiong Y, et al. Among authors: karuppagounder ss. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1635-1640. doi: 10.1073/pnas.1712648115. Epub 2018 Jan 31. Proc Natl Acad Sci U S A. 2018. PMID: 29386392 Free PMC article.
Amelioration of pathologic α-synuclein-induced Parkinson's disease by irisin.
Kam TI, Park H, Chou SC, Van Vranken JG, Mittenbühler MJ, Kim H, A M, Choi YR, Biswas D, Wang J, Shin Y, Loder A, Karuppagounder SS, Wrann CD, Dawson VL, Spiegelman BM, Dawson TM. Kam TI, et al. Among authors: karuppagounder ss. Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2204835119. doi: 10.1073/pnas.2204835119. Epub 2022 Aug 31. Proc Natl Acad Sci U S A. 2022. PMID: 36044549 Free PMC article.
Synaptic Plasticity onto Dopamine Neurons Shapes Fear Learning.
Pignatelli M, Umanah GKE, Ribeiro SP, Chen R, Karuppagounder SS, Yau HJ, Eacker S, Dawson VL, Dawson TM, Bonci A. Pignatelli M, et al. Among authors: karuppagounder ss. Neuron. 2017 Jan 18;93(2):425-440. doi: 10.1016/j.neuron.2016.12.030. Neuron. 2017. PMID: 28103482 Free article.
Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson's Disease.
Kim S, Kwon SH, Kam TI, Panicker N, Karuppagounder SS, Lee S, Lee JH, Kim WR, Kook M, Foss CA, Shen C, Lee H, Kulkarni S, Pasricha PJ, Lee G, Pomper MG, Dawson VL, Dawson TM, Ko HS. Kim S, et al. Among authors: karuppagounder ss. Neuron. 2019 Aug 21;103(4):627-641.e7. doi: 10.1016/j.neuron.2019.05.035. Epub 2019 Jun 26. Neuron. 2019. PMID: 31255487 Free PMC article.
Atp7b-dependent choroid plexus dysfunction causes transient copper deficit and metabolic changes in the developing mouse brain.
Washington-Hughes CL, Roy S, Seneviratne HK, Karuppagounder SS, Morel Y, Jones JW, Zak A, Xiao T, Boronina TN, Cole RN, Bumpus NN, Chang CJ, Dawson TM, Lutsenko S. Washington-Hughes CL, et al. Among authors: karuppagounder ss. PLoS Genet. 2023 Jan 10;19(1):e1010558. doi: 10.1371/journal.pgen.1010558. eCollection 2023 Jan. PLoS Genet. 2023. PMID: 36626371 Free PMC article.
95 results