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Inhibition of histone methyltransferase DOT1L silences ERα gene and blocks proliferation of antiestrogen-resistant breast cancer cells.
Nassa G, Salvati A, Tarallo R, Gigantino V, Alexandrova E, Memoli D, Sellitto A, Rizzo F, Malanga D, Mirante T, Morelli E, Nees M, Åkerfelt M, Kangaspeska S, Nyman TA, Milanesi L, Giurato G, Weisz A. Nassa G, et al. Among authors: gigantino v. Sci Adv. 2019 Feb 6;5(2):eaav5590. doi: 10.1126/sciadv.aav5590. eCollection 2019 Feb. Sci Adv. 2019. PMID: 30775443 Free PMC article.
The nuclear receptor ERβ engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading.
Tarallo R, Giurato G, Bruno G, Ravo M, Rizzo F, Salvati A, Ricciardi L, Marchese G, Cordella A, Rocco T, Gigantino V, Pierri B, Cimmino G, Milanesi L, Ambrosino C, Nyman TA, Nassa G, Weisz A. Tarallo R, et al. Among authors: gigantino v. Genome Biol. 2017 Oct 6;18(1):189. doi: 10.1186/s13059-017-1321-0. Genome Biol. 2017. PMID: 29017520 Free PMC article.
Prospective Evaluation of Radiotherapy-Induced Immunologic and Genetic Effects in Colorectal Cancer Oligo-Metastatic Patients with Lung-Limited Disease: The PRELUDE-1 Study.
Ottaiano A, Petito A, Santorsola M, Gigantino V, Capuozzo M, Fontanella D, Di Franco R, Borzillo V, Buonopane S, Ravo V, Scipilliti E, Totaro G, Serra M, Ametrano G, Penta R, Tatangelo F, Scognamiglio G, Di Mauro A, Di Bonito M, Napolitano M, Scala S, Rea G, Santagata S, Lombardi A, Grimaldi A, Caputo C, Crispo A, Celentano E, De Feo G, Circelli L, Savarese G, Ruggiero R, Perri F, Granata V, Botti G, Caraglia M, Nasti G, Muto P. Ottaiano A, et al. Among authors: gigantino v. Cancers (Basel). 2021 Aug 23;13(16):4236. doi: 10.3390/cancers13164236. Cancers (Basel). 2021. PMID: 34439390 Free PMC article.
Metastatic colorectal cancer and type 2 diabetes: prognostic and genetic interactions.
Ottaiano A, Circelli L, Santorsola M, Savarese G, Fontanella D, Gigantino V, Di Mauro A, Capuozzo M, Zappavigna S, Lombardi A, Perri F, Cascella M, Granata V, Capuozzo M, Nasti G, Caraglia M. Ottaiano A, et al. Among authors: gigantino v. Mol Oncol. 2022 Jan;16(2):319-332. doi: 10.1002/1878-0261.13122. Epub 2021 Nov 19. Mol Oncol. 2022. PMID: 34668636 Free PMC article.
44 results