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Adipose tissue NAD+ biosynthesis is required for regulating adaptive thermogenesis and whole-body energy homeostasis in mice.
Yamaguchi S, Franczyk MP, Chondronikola M, Qi N, Gunawardana SC, Stromsdorfer KL, Porter LC, Wozniak DF, Sasaki Y, Rensing N, Wong M, Piston DW, Klein S, Yoshino J. Yamaguchi S, et al. Among authors: gunawardana sc. Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23822-23828. doi: 10.1073/pnas.1909917116. Epub 2019 Nov 6. Proc Natl Acad Sci U S A. 2019. PMID: 31694884 Free PMC article.
Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch.
Cohen P, Levy JD, Zhang Y, Frontini A, Kolodin DP, Svensson KJ, Lo JC, Zeng X, Ye L, Khandekar MJ, Wu J, Gunawardana SC, Banks AS, Camporez JP, Jurczak MJ, Kajimura S, Piston DW, Mathis D, Cinti S, Shulman GI, Seale P, Spiegelman BM. Cohen P, et al. Among authors: gunawardana sc. Cell. 2014 Jan 16;156(1-2):304-16. doi: 10.1016/j.cell.2013.12.021. Cell. 2014. PMID: 24439384 Free PMC article.
21 results