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Follicular T helper cells shape the HCV-specific CD4+ T cell repertoire after virus elimination.
Smits M, Zoldan K, Ishaque N, Gu Z, Jechow K, Wieland D, Conrad C, Eils R, Fauvelle C, Baumert TF, Emmerich F, Bengsch B, Neumann-Haefelin C, Hofmann M, Thimme R, Boettler T. Smits M, et al. Among authors: wieland d. J Clin Invest. 2020 Feb 3;130(2):998-1009. doi: 10.1172/JCI129642. J Clin Invest. 2020. PMID: 31697649 Free PMC article. Clinical Trial.
Memory-like HCV-specific CD8+ T cells retain a molecular scar after cure of chronic HCV infection.
Hensel N, Gu Z, Sagar, Wieland D, Jechow K, Kemming J, Llewellyn-Lacey S, Gostick E, Sogukpinar O, Emmerich F, Price DA, Bengsch B, Boettler T, Neumann-Haefelin C, Eils R, Conrad C, Bartenschlager R, Grün D, Ishaque N, Thimme R, Hofmann M. Hensel N, et al. Among authors: wieland d. Nat Immunol. 2021 Feb;22(2):229-239. doi: 10.1038/s41590-020-00817-w. Epub 2021 Jan 4. Nat Immunol. 2021. PMID: 33398179
Phenotypic and functional differences of HBV core-specific versus HBV polymerase-specific CD8+ T cells in chronically HBV-infected patients with low viral load.
Schuch A, Salimi Alizei E, Heim K, Wieland D, Kiraithe MM, Kemming J, Llewellyn-Lacey S, Sogukpinar Ö, Ni Y, Urban S, Zimmermann P, Nassal M, Emmerich F, Price DA, Bengsch B, Luxenburger H, Neumann-Haefelin C, Hofmann M, Thimme R. Schuch A, et al. Among authors: wieland d. Gut. 2019 May;68(5):905-915. doi: 10.1136/gutjnl-2018-316641. Epub 2019 Jan 8. Gut. 2019. PMID: 30622109 Free article.
TOX defines the degree of CD8+ T cell dysfunction in distinct phases of chronic HBV infection.
Heim K, Binder B, Sagar, Wieland D, Hensel N, Llewellyn-Lacey S, Gostick E, Price DA, Emmerich F, Vingerhoet H, Kraft ARM, Cornberg M, Boettler T, Neumann-Haefelin C, Zehn D, Bengsch B, Hofmann M, Thimme R. Heim K, et al. Among authors: wieland d. Gut. 2020 Oct 23;70(8):1550-60. doi: 10.1136/gutjnl-2020-322404. Online ahead of print. Gut. 2020. PMID: 33097558 Free PMC article.
256 results