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Targeting RNA with Small Molecules: Identification of Selective, RNA-Binding Small Molecules Occupying Drug-Like Chemical Space.
Rizvi NF, Santa Maria JP Jr, Nahvi A, Klappenbach J, Klein DJ, Curran PJ, Richards MP, Chamberlin C, Saradjian P, Burchard J, Aguilar R, Lee JT, Dandliker PJ, Smith GF, Kutchukian P, Nickbarg EB. Rizvi NF, et al. Among authors: lee jt. SLAS Discov. 2020 Apr;25(4):384-396. doi: 10.1177/2472555219885373. Epub 2019 Nov 8. SLAS Discov. 2020. PMID: 31701793 Free article.
Targeting Xist with compounds that disrupt RNA structure and X inactivation.
Aguilar R, Spencer KB, Kesner B, Rizvi NF, Badmalia MD, Mrozowich T, Mortison JD, Rivera C, Smith GF, Burchard J, Dandliker PJ, Patel TR, Nickbarg EB, Lee JT. Aguilar R, et al. Among authors: lee jt. Nature. 2022 Apr;604(7904):160-166. doi: 10.1038/s41586-022-04537-z. Epub 2022 Mar 30. Nature. 2022. PMID: 35355011 Free PMC article.
The X chromosome in space.
Jégu T, Aeby E, Lee JT. Jégu T, et al. Among authors: lee jt. Nat Rev Genet. 2017 Jun;18(6):377-389. doi: 10.1038/nrg.2017.17. Epub 2017 May 8. Nat Rev Genet. 2017. PMID: 28479596 Review.
Long noncoding RNAs: fresh perspectives into the RNA world.
Yang L, Froberg JE, Lee JT. Yang L, et al. Among authors: lee jt. Trends Biochem Sci. 2014 Jan;39(1):35-43. doi: 10.1016/j.tibs.2013.10.002. Epub 2013 Nov 27. Trends Biochem Sci. 2014. PMID: 24290031 Free PMC article. Review.
Locus-specific targeting to the X chromosome revealed by the RNA interactome of CTCF.
Kung JT, Kesner B, An JY, Ahn JY, Cifuentes-Rojas C, Colognori D, Jeon Y, Szanto A, del Rosario BC, Pinter SF, Erwin JA, Lee JT. Kung JT, et al. Among authors: lee jt. Mol Cell. 2015 Jan 22;57(2):361-75. doi: 10.1016/j.molcel.2014.12.006. Epub 2015 Jan 8. Mol Cell. 2015. PMID: 25578877 Free PMC article.
1,882 results