Luijten M - Search Results

1

Utility of a next generation framework for assessment of genomic damage: A case study using the industrial chemical benzene.

Luijten M, Ball NS, Dearfield KL, Gollapudi BB, Johnson GE, Madia F, Peel L, Pfuhler S, Settivari RS, Ter Burg W, White PA, van Benthem J. Luijten M, et al. Environ Mol Mutagen. 2020 Jan;61(1):94-113. doi: 10.1002/em.22346. Epub 2019 Nov 27. Environ Mol Mutagen. 2020. PMID: 31709603 Free PMC article. Review.

2

Phenacetin acts as a weak genotoxic compound preferentially in the kidney of DNA repair deficient Xpa mice.

Luijten M, Speksnijder EN, van Alphen N, Westerman A, Heisterkamp SH, van Benthem J, van Kreijl CF, Beems RB, van Steeg H. Luijten M, et al. Mutat Res. 2006 Apr 11;596(1-2):143-50. doi: 10.1016/j.mrfmmm.2005.12.011. Epub 2006 Feb 7. Mutat Res. 2006. PMID: 16464479

3

Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach.

Hernández LG, van Steeg H, Luijten M, van Benthem J. Hernández LG, et al. Among authors: luijten m. Mutat Res. 2009 Sep-Dec;682(2-3):94-109. doi: 10.1016/j.mrrev.2009.07.002. Epub 2009 Jul 22. Mutat Res. 2009. PMID: 19631282 Review.

4

Finding maximal transcriptome differences between reprotoxic and non-reprotoxic phthalate responses in rat testis.

Yuan X, Jonker MJ, de Wilde J, Verhoef A, Wittink FR, van Benthem J, Bessems JG, Hakkert BC, Kuiper RV, van Steeg H, Breit TM, Luijten M. Yuan X, et al. Among authors: luijten m. J Appl Toxicol. 2011 Jul;31(5):421-30. doi: 10.1002/jat.1601. Epub 2010 Nov 9. J Appl Toxicol. 2011. PMID: 21061450

5

Transgenic animal models in toxicology: historical perspectives and future outlook.

Boverhof DR, Chamberlain MP, Elcombe CR, Gonzalez FJ, Heflich RH, Hernández LG, Jacobs AC, Jacobson-Kram D, Luijten M, Maggi A, Manjanatha MG, Benthem Jv, Gollapudi BB. Boverhof DR, et al. Among authors: luijten m. Toxicol Sci. 2011 Jun;121(2):207-33. doi: 10.1093/toxsci/kfr075. Epub 2011 Mar 29. Toxicol Sci. 2011. PMID: 21447610 Review.

6

Proliferating primary hepatocytes from the pUR288 lacZ plasmid mouse are valuable tools for genotoxicity assessment in vitro.

Zwart EP, Schaap MM, van den Dungen MW, Braakhuis HM, White PA, van Steeg H, van Benthem J, Luijten M. Zwart EP, et al. Among authors: luijten m. Environ Mol Mutagen. 2012 Jun;53(5):1-8. doi: 10.1002/em.21700. Epub 2012 May 23. Environ Mol Mutagen. 2012. PMID: 22619112

7

Detection of genotoxic and non-genotoxic carcinogens in Xpc(-/-)p53(+/-) mice.

Melis JP, Speksnijder EN, Kuiper RV, Salvatori DC, Schaap MM, Maas S, Robinson J, Verhoef A, van Benthem J, Luijten M, van Steeg H. Melis JP, et al. Among authors: luijten m. Toxicol Appl Pharmacol. 2013 Jan 15;266(2):289-97. doi: 10.1016/j.taap.2012.11.004. Epub 2012 Nov 12. Toxicol Appl Pharmacol. 2013. PMID: 23153559

8

The development of adverse outcome pathways for mutagenic effects for the organization for economic co-operation and development.

Yauk CL, Bishop J, Dearfield KL, Douglas GR, Hales BF, Luijten M, O'Brien JM, Robaire B, Sram R, van Benthem J, Wade MG, White PA, Marchetti F. Yauk CL, et al. Among authors: luijten m. Environ Mol Mutagen. 2013 Mar;54(2):79-81. doi: 10.1002/em.21757. Epub 2013 Jan 28. Environ Mol Mutagen. 2013. PMID: 23355186 No abstract available.

9

A critical appraisal of the process of regulatory implementation of novel in vivo and in vitro methods for chemical hazard and risk assessment.

Piersma AH, Ezendam J, Luijten M, Muller JJ, Rorije E, van der Ven LT, van Benthem J. Piersma AH, et al. Among authors: luijten m. Crit Rev Toxicol. 2014 Nov;44(10):876-94. doi: 10.3109/10408444.2014.940445. Epub 2014 Jul 24. Crit Rev Toxicol. 2014. PMID: 25058877 Review.

10

TP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts.

Kucab JE, van Steeg H, Luijten M, Schmeiser HH, White PA, Phillips DH, Arlt VM. Kucab JE, et al. Among authors: luijten m. Mutat Res. 2015 Mar;773:48-62. doi: 10.1016/j.mrfmmm.2015.01.013. Epub 2015 Jan 30. Mutat Res. 2015. PMID: 25847421 Free PMC article.

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