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Discovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production.
Guidi A, Lalli C, Gimmelli R, Nizi E, Andreini M, Gennari N, Saccoccia F, Harper S, Bresciani A, Ruberti G. Guidi A, et al. Among authors: gimmelli r. PLoS Negl Trop Dis. 2017 Oct 6;11(10):e0005994. doi: 10.1371/journal.pntd.0005994. eCollection 2017 Oct. PLoS Negl Trop Dis. 2017. PMID: 28985236 Free PMC article.
Screening and Phenotypical Characterization of Schistosoma mansoni Histone Deacetylase 8 (SmHDAC8) Inhibitors as Multistage Antischistosomal Agents.
Saccoccia F, Brindisi M, Gimmelli R, Relitti N, Guidi A, Saraswati AP, Cavella C, Brogi S, Chemi G, Butini S, Papoff G, Senger J, Herp D, Jung M, Campiani G, Gemma S, Ruberti G. Saccoccia F, et al. Among authors: gimmelli r. ACS Infect Dis. 2020 Jan 10;6(1):100-113. doi: 10.1021/acsinfecdis.9b00224. Epub 2019 Nov 12. ACS Infect Dis. 2020. PMID: 31661956
Investigating the Antiparasitic Potential of the Marine Sesquiterpene Avarone, Its Reduced form Avarol, and the Novel Semisynthetic Thiazinoquinone Analogue Thiazoavarone.
Imperatore C, Gimmelli R, Persico M, Casertano M, Guidi A, Saccoccia F, Ruberti G, Luciano P, Aiello A, Parapini S, Avunduk S, Basilico N, Fattorusso C, Menna M. Imperatore C, et al. Among authors: gimmelli r. Mar Drugs. 2020 Feb 14;18(2):112. doi: 10.3390/md18020112. Mar Drugs. 2020. PMID: 32075136 Free PMC article.
Comparative metabolic profiling by 1H-NMR spectroscopy analysis reveals the adaptation of S. mansoni from its host to in vitro culture conditions: a pilot study with ex vivo and GSH-supplemented medium-cultured parasites.
Fustaino V, Gimmelli R, Guidi A, Lentini S, Saccoccia F, Petrella G, Cicero DO, Ruberti G. Fustaino V, et al. Among authors: gimmelli r. Parasitol Res. 2022 Apr;121(4):1191-1198. doi: 10.1007/s00436-022-07426-6. Epub 2022 Jan 13. Parasitol Res. 2022. PMID: 35024953
17 results