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Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells.
Molenaar JJ, Ebus ME, Geerts D, Koster J, Lamers F, Valentijn LJ, Westerhout EM, Versteeg R, Caron HN. Molenaar JJ, et al. Among authors: koster j. Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12968-73. doi: 10.1073/pnas.0901418106. Epub 2009 Jun 12. Proc Natl Acad Sci U S A. 2009. PMID: 19525400 Free PMC article.
Silencing of the microtubule-associated proteins doublecortin-like and doublecortin-like kinase-long induces apoptosis in neuroblastoma cells.
Verissimo CS, Molenaar JJ, Meerman J, Puigvert JC, Lamers F, Koster J, Danen EH, van de Water B, Versteeg R, Fitzsimons CP, Vreugdenhil E. Verissimo CS, et al. Among authors: koster j. Endocr Relat Cancer. 2010 Apr 21;17(2):399-414. doi: 10.1677/ERC-09-0301. Print 2010 Jun. Endocr Relat Cancer. 2010. PMID: 20228126
Oncogenic activation of FOXR1 by 11q23 intrachromosomal deletion-fusions in neuroblastoma.
Santo EE, Ebus ME, Koster J, Schulte JH, Lakeman A, van Sluis P, Vermeulen J, Gisselsson D, Øra I, Lindner S, Buckley PG, Stallings RL, Vandesompele J, Eggert A, Caron HN, Versteeg R, Molenaar JJ. Santo EE, et al. Among authors: koster j. Oncogene. 2012 Mar 22;31(12):1571-81. doi: 10.1038/onc.2011.344. Epub 2011 Aug 22. Oncogene. 2012. PMID: 21860421
Copy number defects of G1-cell cycle genes in neuroblastoma are frequent and correlate with high expression of E2F target genes and a poor prognosis.
Molenaar JJ, Koster J, Ebus ME, van Sluis P, Westerhout EM, de Preter K, Gisselsson D, Øra I, Speleman F, Caron HN, Versteeg R. Molenaar JJ, et al. Among authors: koster j. Genes Chromosomes Cancer. 2012 Jan;51(1):10-9. doi: 10.1002/gcc.20926. Epub 2011 Oct 27. Genes Chromosomes Cancer. 2012. PMID: 22034077
871 results