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ST2 deficiency does not impair type 2 immune responses during chronic filarial infection but leads to an increased microfilaremia due to an impaired splenic microfilarial clearance.
Ajendra J, Specht S, Neumann AL, Gondorf F, Schmidt D, Gentil K, Hoffmann WH, Taylor MJ, Hoerauf A, Hübner MP. Ajendra J, et al. Among authors: neumann al. PLoS One. 2014 Mar 24;9(3):e93072. doi: 10.1371/journal.pone.0093072. eCollection 2014. PLoS One. 2014. PMID: 24663956 Free PMC article.
Filarial extract of Litomosoides sigmodontis induces a type 2 immune response and attenuates plaque development in hyperlipidemic ApoE-knockout mice.
Kuehn C, Tauchi M, Furtmair R, Urschel K, Raaz-Schrauder D, Neumann AL, Frohberger SJ, Hoerauf A, Regus S, Lang W, Sagban TA, Stumpfe FM, Achenbach S, Hübner MP, Dietel B. Kuehn C, et al. Among authors: neumann al. FASEB J. 2019 May;33(5):6497-6513. doi: 10.1096/fj.201800947RR. Epub 2019 Feb 26. FASEB J. 2019. PMID: 30807258
S100A8/S100A9 deficiency increases neutrophil activation and protective immune responses against invading infective L3 larvae of the filarial nematode Litomosoides sigmodontis.
Frohberger SJ, Fercoq F, Neumann AL, Surendar J, Stamminger W, Ehrens A, Karunakaran I, Remion E, Vogl T, Hoerauf A, Martin C, Hübner MP. Frohberger SJ, et al. Among authors: neumann al. PLoS Negl Trop Dis. 2020 Feb 27;14(2):e0008119. doi: 10.1371/journal.pntd.0008119. eCollection 2020 Feb. PLoS Negl Trop Dis. 2020. PMID: 32107497 Free PMC article.
ILC2s Control Microfilaremia During Litomosoides sigmodontis Infection in Rag2-/- Mice.
Reichwald JJ, Risch F, Neumann AL, Frohberger SJ, Scheunemann JF, Lenz B, Ehrens A, Strutz W, Schumak B, Hoerauf A, Hübner MP. Reichwald JJ, et al. Among authors: neumann al. Front Immunol. 2022 Jun 9;13:863663. doi: 10.3389/fimmu.2022.863663. eCollection 2022. Front Immunol. 2022. PMID: 35757689 Free PMC article.
30 results