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IL-17 receptor-based signaling and implications for disease.
Li X, Bechara R, Zhao J, McGeachy MJ, Gaffen SL. Li X, et al. Among authors: mcgeachy mj. Nat Immunol. 2019 Dec;20(12):1594-1602. doi: 10.1038/s41590-019-0514-y. Epub 2019 Nov 19. Nat Immunol. 2019. PMID: 31745337 Free PMC article. Review.
The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation.
Gulen MF, Kang Z, Bulek K, Youzhong W, Kim TW, Chen Y, Altuntas CZ, Sass Bak-Jensen K, McGeachy MJ, Do JS, Xiao H, Delgoffe GM, Min B, Powell JD, Tuohy VK, Cua DJ, Li X. Gulen MF, et al. Among authors: mcgeachy mj. Immunity. 2010 Jan 29;32(1):54-66. doi: 10.1016/j.immuni.2009.12.003. Epub 2010 Jan 7. Immunity. 2010. PMID: 20060329 Free PMC article.
Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling.
Ghoreschi K, Laurence A, Yang XP, Tato CM, McGeachy MJ, Konkel JE, Ramos HL, Wei L, Davidson TS, Bouladoux N, Grainger JR, Chen Q, Kanno Y, Watford WT, Sun HW, Eberl G, Shevach EM, Belkaid Y, Cua DJ, Chen W, O'Shea JJ. Ghoreschi K, et al. Among authors: mcgeachy mj. Nature. 2010 Oct 21;467(7318):967-71. doi: 10.1038/nature09447. Nature. 2010. PMID: 20962846 Free PMC article.
Oral-resident natural Th17 cells and γδ T cells control opportunistic Candida albicans infections.
Conti HR, Peterson AC, Brane L, Huppler AR, Hernández-Santos N, Whibley N, Garg AV, Simpson-Abelson MR, Gibson GA, Mamo AJ, Osborne LC, Bishu S, Ghilardi N, Siebenlist U, Watkins SC, Artis D, McGeachy MJ, Gaffen SL. Conti HR, et al. Among authors: mcgeachy mj. J Exp Med. 2014 Sep 22;211(10):2075-84. doi: 10.1084/jem.20130877. Epub 2014 Sep 8. J Exp Med. 2014. PMID: 25200028 Free PMC article.
Integrating p38α MAPK immune signals in nonimmune cells.
Gaffen SL, McGeachy MJ. Gaffen SL, et al. Among authors: mcgeachy mj. Sci Signal. 2015 Mar 3;8(366):fs5. doi: 10.1126/scisignal.aaa8398. Sci Signal. 2015. PMID: 25737584 Free PMC article. Review.
MCPIP1 Endoribonuclease Activity Negatively Regulates Interleukin-17-Mediated Signaling and Inflammation.
Garg AV, Amatya N, Chen K, Cruz JA, Grover P, Whibley N, Conti HR, Hernandez Mir G, Sirakova T, Childs EC, Smithgall TE, Biswas PS, Kolls JK, McGeachy MJ, Kolattukudy PE, Gaffen SL. Garg AV, et al. Among authors: mcgeachy mj. Immunity. 2015 Sep 15;43(3):475-87. doi: 10.1016/j.immuni.2015.07.021. Epub 2015 Aug 25. Immunity. 2015. PMID: 26320658 Free PMC article.
CCAAT/Enhancer-binding protein β promotes pathogenesis of EAE.
Simpson-Abelson MR, Hernandez-Mir G, Childs EE, Cruz JA, Poholek AC, Chattopadhyay A, Gaffen SL, McGeachy MJ. Simpson-Abelson MR, et al. Among authors: mcgeachy mj. Cytokine. 2017 Apr;92:24-32. doi: 10.1016/j.cyto.2017.01.005. Epub 2017 Jan 12. Cytokine. 2017. PMID: 28088614 Free PMC article.
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