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Page 1
Metabolic Profiling Using Stable Isotope Tracing Reveals Distinct Patterns of Glucose Utilization by Physiologically Activated CD8+ T Cells.
Ma EH, Verway MJ, Johnson RM, Roy DG, Steadman M, Hayes S, Williams KS, Sheldon RD, Samborska B, Kosinski PA, Kim H, Griss T, Faubert B, Condotta SA, Krawczyk CM, DeBerardinis RJ, Stewart KM, Richer MJ, Chubukov V, Roddy TP, Jones RG. Ma EH, et al. Among authors: sheldon rd. Immunity. 2019 Nov 19;51(5):856-870.e5. doi: 10.1016/j.immuni.2019.09.003. Epub 2019 Oct 10. Immunity. 2019. PMID: 31747582 Free article.
Methionine Metabolism Shapes T Helper Cell Responses through Regulation of Epigenetic Reprogramming.
Roy DG, Chen J, Mamane V, Ma EH, Muhire BM, Sheldon RD, Shorstova T, Koning R, Johnson RM, Esaulova E, Williams KS, Hayes S, Steadman M, Samborska B, Swain A, Daigneault A, Chubukov V, Roddy TP, Foulkes W, Pospisilik JA, Bourgeois-Daigneault MC, Artyomov MN, Witcher M, Krawczyk CM, Larochelle C, Jones RG. Roy DG, et al. Among authors: sheldon rd. Cell Metab. 2020 Feb 4;31(2):250-266.e9. doi: 10.1016/j.cmet.2020.01.006. Cell Metab. 2020. PMID: 32023446 Free article.
Repression of LKB1 by miR-17∼92 Sensitizes MYC-Dependent Lymphoma to Biguanide Treatment.
Izreig S, Gariepy A, Kaymak I, Bridges HR, Donayo AO, Bridon G, DeCamp LM, Kitchen-Goosen SM, Avizonis D, Sheldon RD, Laister RC, Minden MD, Johnson NA, Duchaine TF, Rudoltz MS, Yoo S, Pollak MN, Williams KS, Jones RG. Izreig S, et al. Among authors: sheldon rd. Cell Rep Med. 2020 May 19;1(2):100014. doi: 10.1016/j.xcrm.2020.100014. Cell Rep Med. 2020. PMID: 32478334 Free PMC article.
1-Methylnicotinamide is an immune regulatory metabolite in human ovarian cancer.
Kilgour MK, MacPherson S, Zacharias LG, Ellis AE, Sheldon RD, Liu EY, Keyes S, Pauly B, Carleton G, Allard B, Smazynski J, Williams KS, Watson PH, Stagg J, Nelson BH, DeBerardinis RJ, Jones RG, Hamilton PT, Lum JJ. Kilgour MK, et al. Among authors: sheldon rd. Sci Adv. 2021 Jan 20;7(4):eabe1174. doi: 10.1126/sciadv.abe1174. Print 2021 Jan. Sci Adv. 2021. PMID: 33523930 Free PMC article.
Itaconate confers tolerance to late NLRP3 inflammasome activation.
Bambouskova M, Potuckova L, Paulenda T, Kerndl M, Mogilenko DA, Lizotte K, Swain A, Hayes S, Sheldon RD, Kim H, Kapadnis U, Ellis AE, Isaguirre C, Burdess S, Laha A, Amarasinghe GK, Chubukov V, Roddy TP, Diamond MS, Jones RG, Simons DM, Artyomov MN. Bambouskova M, et al. Among authors: sheldon rd. Cell Rep. 2021 Mar 9;34(10):108756. doi: 10.1016/j.celrep.2021.108756. Cell Rep. 2021. PMID: 33691097 Free PMC article.
Carbon source availability drives nutrient utilization in CD8+ T cells.
Kaymak I, Luda KM, Duimstra LR, Ma EH, Longo J, Dahabieh MS, Faubert B, Oswald BM, Watson MJ, Kitchen-Goosen SM, DeCamp LM, Compton SE, Fu Z, DeBerardinis RJ, Williams KS, Sheldon RD, Jones RG. Kaymak I, et al. Among authors: sheldon rd. Cell Metab. 2022 Sep 6;34(9):1298-1311.e6. doi: 10.1016/j.cmet.2022.07.012. Epub 2022 Aug 17. Cell Metab. 2022. PMID: 35981545 Free PMC article.
Prior metabolite extraction fully preserves RNAseq quality and enables integrative multi-'omics analysis of the liver metabolic response to viral infection.
Madaj ZB, Dahabieh MS, Kamalumpundi V, Muhire B, Pettinga J, Siwicki RA, Ellis AE, Isaguirre C, Escobar Galvis ML, DeCamp L, Jones RG, Givan SA, Adams M, Sheldon RD. Madaj ZB, et al. Among authors: sheldon rd. RNA Biol. 2023 Jan;20(1):186-197. doi: 10.1080/15476286.2023.2204586. RNA Biol. 2023. PMID: 37095747 Free PMC article.
56 results