Griep A - Search Results

1

NLRP3 inflammasome activation drives tau pathology.

Ising C, Venegas C, Zhang S, Scheiblich H, Schmidt SV, Vieira-Saecker A, Schwartz S, Albasset S, McManus RM, Tejera D, Griep A, Santarelli F, Brosseron F, Opitz S, Stunden J, Merten M, Kayed R, Golenbock DT, Blum D, Latz E, Buée L, Heneka MT. Ising C, et al. Among authors: griep a. Nature. 2019 Nov;575(7784):669-673. doi: 10.1038/s41586-019-1769-z. Epub 2019 Nov 20. Nature. 2019. PMID: 31748742 Free PMC article.

2

PPARγ/RXRα-induced and CD36-mediated microglial amyloid-β phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice.

Yamanaka M, Ishikawa T, Griep A, Axt D, Kummer MP, Heneka MT. Yamanaka M, et al. Among authors: griep a. J Neurosci. 2012 Nov 28;32(48):17321-31. doi: 10.1523/JNEUROSCI.1569-12.2012. J Neurosci. 2012. PMID: 23197723 Free PMC article.

3

Mrp14 deficiency ameliorates amyloid β burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing.

Kummer MP, Vogl T, Axt D, Griep A, Vieira-Saecker A, Jessen F, Gelpi E, Roth J, Heneka MT. Kummer MP, et al. Among authors: griep a. J Neurosci. 2012 Dec 5;32(49):17824-9. doi: 10.1523/JNEUROSCI.1504-12.2012. J Neurosci. 2012. PMID: 23223301 Free PMC article.

4

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.

Heneka MT, Kummer MP, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A, Griep A, Axt D, Remus A, Tzeng TC, Gelpi E, Halle A, Korte M, Latz E, Golenbock DT. Heneka MT, et al. Among authors: griep a. Nature. 2013 Jan 31;493(7434):674-8. doi: 10.1038/nature11729. Epub 2012 Dec 19. Nature. 2013. PMID: 23254930 Free PMC article.

5

Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer's disease.

Venegas C, Kumar S, Franklin BS, Dierkes T, Brinkschulte R, Tejera D, Vieira-Saecker A, Schwartz S, Santarelli F, Kummer MP, Griep A, Gelpi E, Beilharz M, Riedel D, Golenbock DT, Geyer M, Walter J, Latz E, Heneka MT. Venegas C, et al. Among authors: griep a. Nature. 2017 Dec 20;552(7685):355-361. doi: 10.1038/nature25158. Nature. 2017. PMID: 29293211

6

Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease.

Schröder N, Schaffrath A, Welter JA, Putzka T, Griep A, Ziegler P, Brandt E, Samer S, Heneka MT, Kaddatz H, Zhan J, Kipp E, Pufe T, Tauber SC, Kipp M, Brandenburg LO. Schröder N, et al. Among authors: griep a. J Neuroinflammation. 2020 Apr 24;17(1):131. doi: 10.1186/s12974-020-01816-2. J Neuroinflammation. 2020. PMID: 32331524 Free PMC article.

7

Microglial NLRP3 Inflammasome Activation upon TLR2 and TLR5 Ligation by Distinct α-Synuclein Assemblies.

Scheiblich H, Bousset L, Schwartz S, Griep A, Latz E, Melki R, Heneka MT. Scheiblich H, et al. Among authors: griep a. J Immunol. 2021 Oct 15;207(8):2143-2154. doi: 10.4049/jimmunol.2100035. Epub 2021 Sep 10. J Immunol. 2021. PMID: 34507948 Free PMC article.

8

Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes.

Scheiblich H, Dansokho C, Mercan D, Schmidt SV, Bousset L, Wischhof L, Eikens F, Odainic A, Spitzer J, Griep A, Schwartz S, Bano D, Latz E, Melki R, Heneka MT. Scheiblich H, et al. Among authors: griep a. Cell. 2021 Sep 30;184(20):5089-5106.e21. doi: 10.1016/j.cell.2021.09.007. Epub 2021 Sep 22. Cell. 2021. PMID: 34555357 Free PMC article.

9

Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology.

Kummer MP, Ising C, Kummer C, Sarlus H, Griep A, Vieira-Saecker A, Schwartz S, Halle A, Brückner M, Händler K, Schultze JL, Beyer M, Latz E, Heneka MT. Kummer MP, et al. Among authors: griep a. EMBO J. 2021 Dec 15;40(24):e108662. doi: 10.15252/embj.2021108662. Epub 2021 Nov 26. EMBO J. 2021. PMID: 34825707 Free PMC article.

10

NLRP3-directed antisense oligonucleotides reduce microglial immunoactivities in vitro.

Braatz C, Komes MP, Ravichandran KA, de Fragas MG, Griep A, Schwartz S, McManus RM, Heneka MT. Braatz C, et al. Among authors: griep a. J Neurochem. 2024 Oct;168(10):3467-3481. doi: 10.1111/jnc.15778. Epub 2023 Mar 17. J Neurochem. 2024. PMID: 36799439

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