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Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B.
Zyryanova AF, Weis F, Faille A, Alard AA, Crespillo-Casado A, Sekine Y, Harding HP, Allen F, Parts L, Fromont C, Fischer PM, Warren AJ, Ron D. Zyryanova AF, et al. Among authors: allen f. Science. 2018 Mar 30;359(6383):1533-1536. doi: 10.1126/science.aar5129. Science. 2018. PMID: 29599245 Free PMC article.
JACKS: joint analysis of CRISPR/Cas9 knockout screens.
Allen F, Behan F, Khodak A, Iorio F, Yusa K, Garnett M, Parts L. Allen F, et al. Genome Res. 2019 Mar;29(3):464-471. doi: 10.1101/gr.238923.118. Epub 2019 Jan 23. Genome Res. 2019. PMID: 30674557 Free PMC article.
Predicting base editing outcomes using position-specific sequence determinants.
Pallaseni A, Peets EM, Koeppel J, Weller J, Vanderstichele T, Ho UL, Crepaldi L, van Leeuwen J, Allen F, Parts L. Pallaseni A, et al. Among authors: allen f. Nucleic Acids Res. 2022 Apr 8;50(6):3551-3564. doi: 10.1093/nar/gkac161. Nucleic Acids Res. 2022. PMID: 35286377 Free PMC article.
Predicting the mutations generated by repair of Cas9-induced double-strand breaks.
Allen F, Crepaldi L, Alsinet C, Strong AJ, Kleshchevnikov V, De Angeli P, Páleníková P, Khodak A, Kiselev V, Kosicki M, Bassett AR, Harding H, Galanty Y, Muñoz-Martínez F, Metzakopian E, Jackson SP, Parts L. Allen F, et al. Nat Biotechnol. 2018 Nov 27:10.1038/nbt.4317. doi: 10.1038/nbt.4317. Online ahead of print. Nat Biotechnol. 2018. PMID: 30480667 Free PMC article.
Minimal genome-wide human CRISPR-Cas9 library.
Gonçalves E, Thomas M, Behan FM, Picco G, Pacini C, Allen F, Vinceti A, Sharma M, Jackson DA, Price S, Beaver CM, Dovey O, Parry-Smith D, Iorio F, Parts L, Yusa K, Garnett MJ. Gonçalves E, et al. Among authors: allen f. Genome Biol. 2021 Jan 21;22(1):40. doi: 10.1186/s13059-021-02268-4. Genome Biol. 2021. PMID: 33478580 Free PMC article.
Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets.
Dempster JM, Pacini C, Pantel S, Behan FM, Green T, Krill-Burger J, Beaver CM, Younger ST, Zhivich V, Najgebauer H, Allen F, Gonçalves E, Shepherd R, Doench JG, Yusa K, Vazquez F, Parts L, Boehm JS, Golub TR, Hahn WC, Root DE, Garnett MJ, Tsherniak A, Iorio F. Dempster JM, et al. Among authors: allen f. Nat Commun. 2019 Dec 20;10(1):5817. doi: 10.1038/s41467-019-13805-y. Nat Commun. 2019. PMID: 31862961 Free PMC article.
724 results