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In vitro and in vivo properties of therapeutic oligonucleotides containing non-chiral 3' and 5' thiophosphate linkages.
Nucleic Acids Res. 2020 Jan 10;48(1):63-74. doi: 10.1093/nar/gkz1099.
Nucleic Acids Res. 2020.
PMID: 31754711
Free PMC article.
Investigating discovery strategies and pharmacological properties of stereodefined phosphorodithioate LNA gapmers.
Duschmalé J, Schäublin A, Funder E, Schmidt S, Kiełpiński ŁJ, Nymark H, Jensen K, Koch T, Duschmalé M, Koller E, Møller MR, Schadt S, Husser C, Brink A, Sewing S, Minz T, Wengel J, Bleicher K, Li M.
Duschmalé J, et al. Among authors: duschmale m.
Mol Ther Nucleic Acids. 2022 Jun 22;29:176-188. doi: 10.1016/j.omtn.2022.06.010. eCollection 2022 Sep 13.
Mol Ther Nucleic Acids. 2022.
PMID: 35860384
Free PMC article.
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Evaluation of bovine milk extracellular vesicles for the delivery of locked nucleic acid antisense oligonucleotides.
Grossen P, Portmann M, Koller E, Duschmalé M, Minz T, Sewing S, Pandya NJ, van Geijtenbeek SK, Ducret A, Kusznir EA, Huber S, Berrera M, Lauer ME, Ringler P, Nordbo B, Jensen ML, Sladojevich F, Jagasia R, Alex R, Gamboni R, Keller M.
Grossen P, et al. Among authors: duschmale m.
Eur J Pharm Biopharm. 2021 Jan;158:198-210. doi: 10.1016/j.ejpb.2020.11.012. Epub 2020 Nov 26.
Eur J Pharm Biopharm. 2021.
PMID: 33248268
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Investigating receptor-mediated antibody transcytosis using blood-brain barrier organoid arrays.
Simonneau C, Duschmalé M, Gavrilov A, Brandenberg N, Hoehnel S, Ceroni C, Lassalle E, Kassianidou E, Knoetgen H, Niewoehner J, Villaseñor R.
Simonneau C, et al. Among authors: duschmale m.
Fluids Barriers CNS. 2021 Sep 20;18(1):43. doi: 10.1186/s12987-021-00276-x.
Fluids Barriers CNS. 2021.
PMID: 34544422
Free PMC article.
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