Gotthardt M - Search Results

1

Resolving titin's lifecycle and the spatial organization of protein turnover in mouse cardiomyocytes.

Rudolph F, Hüttemeister J, da Silva Lopes K, Jüttner R, Yu L, Bergmann N, Friedrich D, Preibisch S, Wagner E, Lehnart SE, Gregorio CC, Gotthardt M. Rudolph F, et al. Among authors: gotthardt m. Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25126-25136. doi: 10.1073/pnas.1904385116. Epub 2019 Nov 22. Proc Natl Acad Sci U S A. 2019. PMID: 31757849 Free PMC article.

2

The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system.

Bang ML, Centner T, Fornoff F, Geach AJ, Gotthardt M, McNabb M, Witt CC, Labeit D, Gregorio CC, Granzier H, Labeit S. Bang ML, et al. Among authors: gotthardt m. Circ Res. 2001 Nov 23;89(11):1065-72. doi: 10.1161/hh2301.100981. Circ Res. 2001. PMID: 11717165

3

Induction and myofibrillar targeting of CARP, and suppression of the Nkx2.5 pathway in the MDM mouse with impaired titin-based signaling.

Witt CC, Ono Y, Puschmann E, McNabb M, Wu Y, Gotthardt M, Witt SH, Haak M, Labeit D, Gregorio CC, Sorimachi H, Granzier H, Labeit S. Witt CC, et al. Among authors: gotthardt m. J Mol Biol. 2004 Feb 6;336(1):145-54. doi: 10.1016/j.jmb.2003.12.021. J Mol Biol. 2004. PMID: 14741210

4

M line-deficient titin causes cardiac lethality through impaired maturation of the sarcomere.

Weinert S, Bergmann N, Luo X, Erdmann B, Gotthardt M. Weinert S, et al. Among authors: gotthardt m. J Cell Biol. 2006 May 22;173(4):559-70. doi: 10.1083/jcb.200601014. Epub 2006 May 15. J Cell Biol. 2006. PMID: 16702235 Free PMC article.

5

Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy.

Radke MH, Peng J, Wu Y, McNabb M, Nelson OL, Granzier H, Gotthardt M. Radke MH, et al. Among authors: gotthardt m. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3444-9. doi: 10.1073/pnas.0608543104. Epub 2007 Feb 20. Proc Natl Acad Sci U S A. 2007. PMID: 17360664 Free PMC article.

6

The tight junction protein CAR regulates cardiac conduction and cell-cell communication.

Lisewski U, Shi Y, Wrackmeyer U, Fischer R, Chen C, Schirdewan A, Jüttner R, Rathjen F, Poller W, Radke MH, Gotthardt M. Lisewski U, et al. Among authors: gotthardt m. J Exp Med. 2008 Sep 29;205(10):2369-79. doi: 10.1084/jem.20080897. Epub 2008 Sep 15. J Exp Med. 2008. PMID: 18794341 Free PMC article.

7

Enhancement of the endothelial NO synthase attenuates experimental diastolic heart failure.

Westermann D, Riad A, Richter U, Jäger S, Savvatis K, Schuchardt M, Bergmann N, Tölle M, Nagorsen D, Gotthardt M, Schultheiss HP, Tschöpe C. Westermann D, et al. Among authors: gotthardt m. Basic Res Cardiol. 2009 Sep;104(5):499-509. doi: 10.1007/s00395-009-0014-6. Epub 2009 Mar 3. Basic Res Cardiol. 2009. PMID: 19255799

8

Titin visualization in real time reveals an unexpected level of mobility within and between sarcomeres.

da Silva Lopes K, Pietas A, Radke MH, Gotthardt M. da Silva Lopes K, et al. Among authors: gotthardt m. J Cell Biol. 2011 May 16;193(4):785-98. doi: 10.1083/jcb.201010099. Epub 2011 May 9. J Cell Biol. 2011. PMID: 21555460 Free PMC article.

9

Axial tubule junctions control rapid calcium signaling in atria.

Brandenburg S, Kohl T, Williams GS, Gusev K, Wagner E, Rog-Zielinska EA, Hebisch E, Dura M, Didié M, Gotthardt M, Nikolaev VO, Hasenfuss G, Kohl P, Ward CW, Lederer WJ, Lehnart SE. Brandenburg S, et al. Among authors: gotthardt m. J Clin Invest. 2016 Oct 3;126(10):3999-4015. doi: 10.1172/JCI88241. Epub 2016 Sep 19. J Clin Invest. 2016. PMID: 27643434 Free PMC article.

10

Microtubule cytoskeleton regulates Connexin 43 localization and cardiac conduction in cardiomyopathy caused by mutation in A-type lamins gene.

Macquart C, Jüttner R, Morales Rodriguez B, Le Dour C, Lefebvre F, Chatzifrangkeskou M, Schmitt A, Gotthardt M, Bonne G, Muchir A. Macquart C, et al. Among authors: gotthardt m. Hum Mol Genet. 2019 Dec 15;28(24):4043-4052. doi: 10.1093/hmg/ddy227. Hum Mol Genet. 2019. PMID: 29893868 Free article.

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